AG Scientific/Zaragozic acid A, Squalestatin S1, SQ1/Z-2583/5 mg
商品编号：
Z-2583-5mg
品牌：
agscientific
市场价：
¥12015.40
美元价：
7209.24
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
*Please inquire the availability for this product. Zaragozic acid A is the major metabolite of a class of unusual bicyclic tricarboxylic acids, produced by a number of fungi in the genera Curvularia, Exserohilum, Setosphaeria and others, discovered at Merck and Glaxo in the early 1990s. In nature, zaragozic acid A acts as a broad spectrum antifungal but its mode of action as an inhibitor of squalene synthase, involved in sterol biosynthesis, led to investigation as a cholesterol lowering agent.
Additional Information
| Synonyms | Squalestatin A, Squalestatin S1, L 694599 |
|---|---|
| Product # | Z-2583 |
| CAS # | 142561-96-4 |
| Chemical Name | (1S,3S,4S,5R,6R,7R)-1-[(4S,5R)-4-ACETOXY-5-METHYL-3-METHYLENE-6-PHENYLHEXYL]-6-([(2E,4S,6S)-4,6-DIMETHYL-2-OCTENOYL]OXY)-4,7-DIHYDROXY-2,8-DIOXABICYCLO[3.2.1]OCTANE-3,4,5-TRICARBOXYLIC ACID |
| Formula | C35H46O14 |
| MW | 690.7 |
| Appearance | White to light tan solid |
| Purity | >98% by HPLC |
| Solubility | Soluble in ethanol (10 mg/ml), methanol, DMF, DMSO (10 mg/ml), and water (moderate) |
| Boiling Point | 850.1 °C at 760 mmHg |
| Storage Temp | -20 |
| Therapeutic Area | Infectious Diseases |
| Use | Zaragozic acid A acts as a broad spectrum antifungal |
Additional Information
| InChI | InChI=1S/C35H46O14/c1-7-19(2)17-20(3)13-14-25(37)47-28-27(38)33(48-29(30(39)40)34(45,31(41)42)35(28,49-33)32(43)44)16-15-21(4)26(46-23(6)36)22(5)18-24-11-9-8-10-12-24/h8-14,19-20,22,26-29,38,45H,4,7,15-18H2,1-3,5-6H3,(H,39,40)(H,41,42)(H,43,44)/b14-13+/t19-,20+,22+,26+,27+,28+,29+,33-,34+,35-/m0/s1 |
|---|---|
| SMILES | CC[C@H](C)C[C@H](C)/C=C/C(=O)O[C@@H]1[C@H]([C@]2(O[C@@H]([C@]([C@@]1(O2)C(=O)O)(C(=O)O)O)C(=O)O)CCC(=C)[C@H]([C@H](C)Cc3ccccc3)OC(=O)C)O |
品牌介绍
AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。
