AG Scientific/Zaragozic acid A, Squalestatin S1, SQ1/Z-2583/1 mg
商品编号：
Z-2583-1mg
品牌：
agscientific
市场价：
¥3436.00
美元价：
2577.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
*PleaseinquiretheavailABIlityforthisproduct.ZaragozicacidAisthemajormetaboliteofaclassofunusualbicyclictricarboxylicacids,producedbyanumberoffungiinthegeneraCurvularia,ExSEROhilum,Setosphaeriaandothers,discoveredatMerckandGlaxointheearly1990s.Innature,zaragozicacidAactsasabroadspectrumantifungalbutitsmodeofactionasaninhibitorofsqualenesynthase,involvedinsterolbiosynthesis,ledtoinvestigationasacholesterolloweringagent.
AdditionalInformation
| Synonyms | SqualestatinA,SqualestatinS1,L694599 |
|---|---|
| Product# | Z-2583 |
| CAS# | 142561-96-4 |
| ChemicalName | (1S,3S,4S,5R,6R,7R)-1-[(4S,5R)-4-ACETOXY-5-METHYL-3-METHYLENE-6-PHENYLHEXYL]-6-([(2E,4S,6S)-4,6-DIMETHYL-2-OCTENOYL]OXY)-4,7-DIHYDROXY-2,8-DIOXABICYCLO[3.2.1]OCTANE-3,4,5-TRICARBOXYLICACID |
| Formula | C35H46O14 |
| MW | 690.7 |
| Appearance | Whitetolighttansolid |
| Purity | >98%byHPLC |
| Solubility | Solubleinethanol(10mg/ml),methanol,DMF,DMSO(10mg/ml),andwater(moderate) |
| BoilingPoint | 850.1°Cat760mmHg |
| StorageTemp | -20 |
| TherapeuticArea | InfectiousDiseases |
| Use | ZaragozicacidAactsasabroadspectrumantifungal |
| InChI | InChI=1S/C35H46O14/c1-7-19(2)17-20(3)13-14-25(37)47-28-27(38)33(48-29(30(39)40)34(45,31(41)42)35(28,49-33)32(43)44)16-15-21(4)26(46-23(6)36)22(5)18-24-11-9-8-10-12-24/h8-14,19-20,22,26-29,38,45H,4,7,15-18H2,1-3,5-6H3,(H,39,40)(H,41,42)(H,43,44)/b14-13+/t19-,20+,22+,26+,27+,28+,29+,33-,34+,35-/m0/s1 |
|---|---|
| SMILES | CC[C@H](C)C[C@H](C)/C=C/C(=O)O[C@@H]1[C@H]([C@]2(O[C@@H]([C@]([C@@]1(O2)C(=O)O)(C(=O)O)O)C(=O)O)CCC(=C)[C@H]([C@H](C)Cc3ccccc3)OC(=O)C)O |
