AG Scientific/UNC-2170/M-2753/5 mg
商品编号：
M-2753-5mg
品牌：
agscientific
市场价：
¥1964.60
美元价：
1473.45
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
TheDNAdamageresponseprotein53BP1utilizesitstandemtudordomaintorecognizedimethylatedlysine20onhistone(H4K20me2),amodificationassociatedwithdouble-strandDNAbreaks.UNC-2170,identifiedbyscreening,wasfoundtobeamicroMligandfor53BP1whichalsodemonstratedatleast17-foldselectivityfor53BP1overothermethyl-lysinebindingproteins.Thecompoundfunctionsasa53BP1antagoNISTincelllysatesandsuppressesclassswitchrecombinationinwholecells,aprocessrequiringafunctioning53BP1tudordomain1.
References:
1.MTPerfettietal.ACSChem.Biol.201510:1072
AdditionalInformation
| Synonyms | 3-Bromo-N-(3-(tert-butylamino)propyl)benzamide,hydrochloride |
|---|---|
| Product# | M-2753 |
| CAS# | 1648707-58-7 |
| Formula | C14H21BrN2O.HCl |
| MW | 349.7 |
| Appearance | whitepowder |
| Purity | >98% |
| Solubility | MaybedissolvedinDMSOorwater |
| MeltingPoint | 162-164°C |
| StorageTemp | -20°C |
