AG Scientific/Tetromycin B/T-2621/2.5 mg
商品编号：
T-2621-2.5mg
品牌：
agscientific
市场价：
¥19335.80
美元价：
11601.48
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
*PleaseinquiretheavailABIlityforthisproduct.TetromycinBisanunusualtetronicacid,structurallyrelatedtokijanimicin,chlorothricin,saccharocarcin,tetrocarcinandversipelostatin.TetromycinBhaspronouncedactivityagainstantibioticsusceptIBLeandresistantGrampositivebacteriaincludingMRSA.Limitedavailabilityhasrestrictedfurtherinvestigationofthismetaboliteintheliterature.Severalmembersofthisclasshavereceivedconsiderableliteraturefocus.VersipelostatininhibitstranscriptionfromthepromoterofGRP78,agenethatisactivatedaspartofastresssignallingpathwayunderglucosedeprivationresultinginunfoldedproteinresponse(UPR).TheUPR-inhibitoryactionisseenonlyinconditionsofglucosedeprivationandcausesselectiveandmassivekillingoftheglucose-deprivedcells.TetrocarcinAappearstotargetthephosphatidylinositide-3"-kinase/Aktsignallingpathway.
AdditionalInformation
| Product# | T-2621 |
|---|---|
| CAS# | 180027-84-3 |
| Formula | C34H46O5 |
| MW | 534.7 |
| Appearance | Lighttansolid |
| Purity | >99%byHPLC |
| Solubility | Solubleinethanol,methanol,DMF,DMSO,andwater(moderately) |
| BoilingPoint | 680.0±55.0°Cat760mmHg |
| StorageTemp | -20°C |
| TherapeuticArea | InfectiousDiseases |
| Use | TetromycinBhasdisplayedpronouncedactivityagainstantibioticsusceptibleandresistantGrampositivebacteriaincludingMRSA |
| MDLNumber | MFCD00950447 |
|---|---|
| InChI | InChI=1S/C34H46O5/c1-18-10-9-11-19(2)27-21(4)14-24-25(35)13-12-20(3)28(24)33(27,8)29(36)26-30(37)34(39-31(26)38)17-23(6)22(5)16-32(34,7)15-18/h11,14-16,20,23-25,27-28,35,37H,9-10,12-13,17H2,1-8H3/b18-15+,19-11+ |
| SMILES | CC1CCC(C2C1C3(C(/C(=C/CC/C(=C/C4(C=C(C(CC45C(=C(C3=O)C(=O)O5)O)C)C)C)/C)/C)C(=C2)C)C)O |
