AG Scientific/Tetromycin A/T-2619/0.5 mg
商品编号：
T-2619-0.5mg
品牌：
agscientific
市场价：
¥5687.00
美元价：
3412.20
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
*Please inquire the availability for this product. Tetromycin A is an unusual tetronic acid, structurally related to kijanimicin, chlorothricin, saccharocarcin, tetrocarcin and versipelostatin. Tetromycin A has pronounced activity against antibiotic susceptible and resistant Gram positive bacteria including MRSA. Limited availability has restricted further investigation of this metabolite in the literature. Several members of this class have received considerable literature focus. Versipelostatin inhibits transcription from the promoter of GRP78, a gene that is activated as part of a stress signalling pathway under glucose deprivation resulting in unfolded protein response (UPR). The UPR-inhibitory action is seen only in conditions of glucose deprivation and causes selective and massive killing of the glucose-deprived cells. Tetrocarcin A appears to target the phosphatidylinositide-3'-kinase/Akt signalling pathway.
Additional Information
| Product # | T-2619 |
|---|---|
| CAS # | 180027-83-2 |
| Formula | C36H48O6 |
| MW | 576.8 |
| Appearance | Light tan solid |
| Purity | >99% by HPLC |
| Solubility | Soluble in ethanol, DMSO, DMF, methanol, and water (moderately) |
| Boiling Point | 684.1±55.0 °C at 760 mmHg |
| Storage Temp | -20°C |
| Therapeutic Area | Infectious Diseases |
| Use | An antibiotic against antibiotic resistant and susceptible gram-positive bacteria including MRSA |
Additional Information
| MDL Number | MFCD00950446 |
|---|---|
| InChI | InChI=1S/C36H48O6/c1-19-11-10-12-20(2)29-22(4)15-26-27(41-25(7)37)14-13-21(3)30(26)35(29,9)31(38)28-32(39)36(42-33(28)40)18-24(6)23(5)17-34(36,8)16-19/h12,15-17,21,24,26-27,29-30,39H,10-11,13-14,18H2,1-9H3/b19-16+,20-12+ |
| SMILES | CC1CCC(C2C1C3(C(/C(=C/CC/C(=C/C4(C=C(C(CC45C(=C(C3=O)C(=O)O5)O)C)C)C)/C)/C)C(=C2)C)C)OC(=O)C |
品牌介绍
AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。
