AG Scientific/Swainsonine/S-3351/5 mg
商品编号：
S-3351-5mg
品牌：
agscientific
市场价：
¥8000.00
美元价：
4800.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Swainsonineisknowntobeproducedbyfungalsymbiontsofplants(endophytes),plantpathogens,andinsectpathogens.Itisanindolizidinealkaloid,amannofuranoseanalog,thatspecificallyinhibitsa-mannosidaseIIintheGolgiapparatus,disruptingtheendomembranesystemofthecell.Swainsonineisunderconsiderationasacomponentofchemotherapeutictreatmentsforsomecancers. Swainsonine"sactivityagainsttumorsisattributedtoitsstimulationofmacrophages.Inmice,swainsoninereducesthetoxicityofdoxorubicin,suggestingthatswainsoninemightenableuseofhigherdosesofdoxorubicin.Swainsoninemaypromoterestorationofbonemarrowdamagedbysometypesofcancertreatments.
AdditionalInformation
| Synonyms | SWAINSONINE,8A,B-INDOLIZIDINE-1,2A,8B-TRIOL,(1S,2R,8R,8aR)-octahydro-1,2,8indolizinetriol,Tridolgosir,(1S,2R,8R,8aR)-octahydroindolizine-1,2,8-triol,SwainMoia,D-Swainsonine |
|---|---|
| Product# | S-3351 |
| CAS# | 72741-87-8 |
| Formula | C8H15NO3 |
| MW | 173.20 |
| Appearance | Beigelyophilizedpowder |
| Purity | 98% |
| Solubility | Water:Clearcolorlesssolubilityat10mg/ml;Methanol:Clearcolorlesssolutionat5mg/ml |
| StorageTemp | Storeinafreezeruponarrival,at-10°Cto-25°C |
| TherapeuticArea | Immunotherapy |
