AG Scientific/Swainsonine/S-3351/1 mg
商品编号：
S-3351-1mg
品牌：
agscientific
市场价：
¥2000.00
美元价：
1500.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Swainsonine is known to be produced by fungal symbionts of plants (endophytes), plant pathogens, and insect pathogens. It is an indolizidine alkaloid, a mannofuranose analog, that specifically inhibits a-mannosidase II in the Golgi apparatus, disrupting the endomembrane system of the cell. Swainsonine is under consideration as a component of chemotherapeutic treatments for some cancers. Swainsonine's activity against tumors is attributed to its stimulation of macrophages. In mice, swainsonine reduces the toxicity of doxorubicin, suggesting that swainsonine might enable use of higher doses of doxorubicin. Swainsonine may promote restoration of bone marrow damaged by some types of cancer treatments.
Additional Information
| Synonyms | SWAINSONINE, 8A,B-INDOLIZIDINE-1,2A,8B-TRIOL, (1S,2R,8R,8aR)-octahydro-1,2,8indolizinetriol, Tridolgosir, (1S,2R,8R,8aR)-octahydroindolizine-1,2,8-triol, SwainMoia, D-Swainsonine |
|---|---|
| Product # | S-3351 |
| CAS # | 72741-87-8 |
| Formula | C8H15NO3 |
| MW | 173.20 |
| Appearance | Beige lyophilized powder |
| Purity | 98% |
| Solubility | Water: Clear colorless solubility at 10mg/ml; Methanol: Clear colorless solution at 5 mg/ml |
| Storage Temp | Store in a freezer upon arrival, at -10°C to -25°C |
| Therapeutic Area | Immunotherapy |
Additional Information
品牌介绍
AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。
