AG Scientific/Rebeccamycin/R-2587/2.5 mg
商品编号：
R-2587-2.5mg
品牌：
agscientific
市场价：
¥16440.60
美元价：
9864.36
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
*Please inquire the availability for this product. Rebeccamycin is an indolocarbazole isolated from Lechevalieria aerocolonigenes. Rebeccamycin displays selective antitumor activity against several cell lines. Rebeccamycin's primary mechanism of action is via strong DNA intercalation resulting in the potent catalytic inhibition of both topoisomerases I and II. Analogues of rebeccamycin have been tested in clinical trials for cancer therapy.
Additional Information
| Product # | R-2587 |
|---|---|
| CAS # | 93908-02-2 |
| Formula | C27H21Cl2N3O7 |
| MW | 570.4 |
| Appearance | Dull yellow lyophilisate |
| Purity | >99% by HPLC |
| Solubility | Soluble in DMSO (=3 mg/ml), THF, and methanol (=02 mg/ml) |
| Storage Temp | -20°C |
| Therapeutic Area | Oncological Disorders |
| Use | An indolocarbazole topoisomerase inhibitor shows significant antitumor properties |
Additional Information
| MDL Number | MFCD01718312 |
|---|---|
| InChI | InChI=1S/C27H21Cl2N3O7/c1-38-24-13(8-33)39-27(23(35)22(24)34)32-20-10(5-3-7-12(20)29)15-17-16(25(36)31-26(17)37)14-9-4-2-6-11(28)18(9)30-19(14)21(15)32/h4-7,13,22-24,27,30,33-35H,8H2,1H3,(H,31,36,37)/t13-,22-,23-,24-,27-/m1/s1 |
| SMILES | CO[C@@H]1[C@H](O[C@H]([C@@H]([C@H]1O)O)n2c3c(cccc3Cl)c4c2c5c(c6cccc(c6[nH]5)Cl)c7c4C(=O)NC7=O)CO |
品牌介绍
AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。
