AG Scientific/Saccharoccin B/S-2745/0.5 mg
商品编号：
S-2745-0.5mg
品牌：
agscientific
市场价：
¥6100.60
美元价：
3660.36
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
*PleaseinquiretheavailABIlityforthisproduct.SaccharocarcinBisanunusualtetronicacidstructurallyrelatedtokijanimicin,chlorothricin,tetrocarcinsandversipelostatin,whichhaspronouncedactivityagainstGrampositivebacteriaandChlamydiatrachomatis.Limitedavailabilityhasrestrictedfurtherinvestigationofthismetabolite,howeverseveralmembersofthisclasshavereceivedconsiderableliteraturefocus.VersipelostatininhibitstranscriptionfromthepromoterofGRP78,agenethatisactivatedaspartofastresssignallingpathwayunderglucosedeprivationresultinginunfoldedproteinresponse(UPR),causingdeathofglucose-deprivedcells.TetrocarcinAappearstotargetthephosphatidylinositide-3"-kinase/Aktsignallingpathway.
AdditionalInformation
| Product# | S-2745 |
|---|---|
| CAS# | 158475-33-3 |
| Formula | C68H103NO20 |
| MW | 1254.6 |
| Appearance | Whitesolid |
| Purity | >99%byHPLC |
| Solubility | Solubleinwater(limitedly),ethanol,DMSO,methanol,andDMF |
| StorageTemp | -20°C |
| TherapeuticArea | InfectiousDiseases |
| Use | Anunusualtetronicacidwithinhibitoryeffectsongrampositivebacteria |
| MDLNumber | MFCD14635442 |
|---|---|
| InChI | InChI=1S/C68H103NO20/c1-15-16-42-17-18-43-25-35(6)58(88-54-30-66(13,78)62(40(11)83-54)69-41(12)70)33(4)23-31(2)45-20-19-44-56(67(45,14)63(75)55-64(76)68(43,29-42)89-65(55)77)32(3)24-34(5)59(44)85-53-28-49(84-50-22-21-46(71)36(7)79-50)61(39(10)82-53)87-52-27-48(73)60(38(9)81-52)86-51-26-47(72)57(74)37(8)80-51/h17-20,23,25,32-34,36-40,42-54,56-62,71-74,76,78H,15-16,21-22,24,26-30H2,1-14H3,(H,69,70)/b31-23+,35-25+/t32-,33?,34-,36-,37+,38+,39+,40-,42-,43-,44-,45-,46+,47+,48+,49+,50-,51+,52+,53+,54-,56+,57+,58-,59-,60+,61+,62-,66-,67+,68-/m0/s1 |
| SMILES | CCC[C@@H]1C[C@]23[C@@H](C=C1)/C=C(/[C@H](C(/C=C(/[C@@H]4C=C[C@H]5[C@H]([C@@]4(C(=O)C(=C2O)C(=O)O3)C)[C@H](C[C@@H]([C@@H]5O[C@@H]6C[C@H]([C@@H]([C@H](O6)C)O[C@@H]7C[C@H]([C@@H]([C@H](O7)C)O[C@@H]8C[C@H]([C@@H]([C@H](O8)C)O)O)O)O[C@H]9CC[C@H]([C@@H](O9)C)O)C)C)C)C)O[C@H]1C[C@]([C@H]([C@@H](O1)C)NC(=O)C)(C)O)C |
