AG Scientific/Ridaforolimus/R-2597/5 mg
商品编号：
R-2597-5mg
品牌：
agscientific
市场价：
¥11567.20
美元价：
6940.32
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
*PleaseinquiretheavailABIlityforthisproduct.Ridaforolimusisasemisyntheticmacrocycliclactonepreparedfromrapamycinbyselectivealkylationofthe42-hydroxygroupwithadimethylphosphinatemoiety.Likealltacrolimusanalogues,ridaforolimusbindstoreceptorprotein,FKBP12.ThecomplexthenbindstomTORpreventingitsinteractionwithtargetproteins.Ridaforolimusisextensivelycitedintheliteraturewithover70citations.
AdditionalInformation
| Synonyms | AP23573,MK8669,42-Dimethylphosphinate-rapamycin |
|---|---|
| Product# | R-2597 |
| CAS# | 572924-54-0 |
| Formula | C53H84NO14P |
| MW | 990.2 |
| Appearance | Whitesolid |
| Purity | >95%byHPLC |
| BoilingPoint | 996.2±75.0°Cat760mmHg |
| TherapeuticArea | OncologicalDisorders |
| Use | RidaforolimusaselectiveFRAP(mTOR)inhibitorshowsantiproliferativeactivity |
| MDLNumber | MFCD13184816 |
|---|---|
| InChI | InChI=1S/C53H84NO14P/c1-32-18-14-13-15-19-33(2)44(63-8)30-40-23-21-38(7)53(61,67-40)50(58)51(59)54-25-17-16-20-41(54)52(60)66-45(35(4)28-39-22-24-43(46(29-39)64-9)68-69(11,12)62)31-42(55)34(3)27-37(6)48(57)49(65-10)47(56)36(5)26-32/h13-15,18-19,27,32,34-36,38-41,43-46,48-49,57,61H,16-17,20-26,28-31H2,1-12H3/b15-13+,18-14+,33-19+,37-27+/t32-,34-,35-,36-,38-,39+,40+,41+,43-,44+,45+,46-,48-,49+,53-/m1/s1 |
| SMILES | C[C@@H]1CCC2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)OP(=O)(C)C)C)/C)O)OC)C)C)/C)OC |
