AG Scientific/PBIT，JARID1赖氨酸脱甲基酶抑制剂/P-3329/25毫克
商品编号：
P-3329-25mg
品牌：
agscientific
市场价：
¥4611.40
美元价：
3458.55
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
PBIT (2514-30-9) is a potent and selective inhibitor of JARID1 (IC50 = 3, 4.9 and 6 μM for JARID1B, 1A and 1C, respectively). The JARID1 (Jumonji AT-Rich Interactive Domain 1) family of lysine demethylases demethylates the trimethylated lysine 27 in histone H3 (H3K4me3). PBIT is selective for JARID1 over UTX and JMJD3. Treatment of cells with PBIT inhibits the demethylation of H3K4me3. It inhibits proliferation of breast cancer cell lines expressing high levels of JARID1B1.
Additional Information
| Product # | P-3329 |
|---|---|
| CAS # | 2514-30-9 |
| Chemical Name | 2-(4-Methylphenyl)-1,2-benzisothiazol-3(2H)-one |
| Formula | C14H11NOS |
| MW | 241.31 |
| Appearance | Off-white solid |
| Purity | 98% by TLC NMR (Conforms) |
| Solubility | Soluble in DMSO (up to 24 mg/ml) or in Ethanol (up to 5 mg/ml) |
| Storage Temp | -20°C (des.) |
Additional Information
品牌介绍
AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。
