AG Scientific/Nosiheptide/N-2611/1 mg
商品编号：
N-2611-1mg
品牌：
agscientific
市场价：
¥2070.00
美元价：
1552.50
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
*PleaseinquiretheavailABIlityforthisproduct.Nosiheptideisabicyclicthiopeptideantibioticproducedbyseveralspeciesofactinomycetes,notablyStreptomyces,firstreportedbyJapaneseresearchersin1970.Unlikeotherbicyclicthiopeptidessuchasthiostrepton,thesecondmacrocyclicringislinkedbyrelativelyfragilelactoneandthiolactonebridgestothecorecyclicpeptide.Nosiheptidehasbroadspectrumantibacterialactivity,andhasrecentlydemonstratedaprolongedpost-antibioticeffectinbothnosocomialandcommunity-acquiredMRSAcomparedwithvancomycin.Despiteitslonghistoryinanimalhealth,nosiheptidehasnotbeenextensivelystudiedandisregardedasa"lostantibiotic"largelyescapingintensiveinvestigationforhumanapplication.
AdditionalInformation
| Synonyms | Nosiheptine,Multhiomycin,Primofax,RP9671 |
|---|---|
| Product# | N-2611 |
| CAS# | 56377-79-8 |
| Formula | C51H43N13O12S6 |
| MW | 1222.4 |
| Appearance | Yellowsolid |
| Purity | >95%byHPLC |
| StorageTemp | -20°C |
| TherapeuticArea | InfectiousDiseases |
| Use | Nosiheptidehasbroadspectrumantibacterialactivity |
| MDLNumber | MFCD00867479 |
|---|---|
| InChI | InChI=1S/C51H43N13O12S6/c1-5-23-46-60-28(14-79-46)41(70)56-25-10-33(67)50(74)76-11-21-7-6-8-24-34(21)18(2)35(54-24)51(75)82-17-31(57-42(71)29-15-80-47(25)61-29)48-58-26(12-78-48)37-22(45-59-30(13-77-45)43(72)64-36(20(4)65)44(73)55-23)9-32(66)38(63-37)49-62-27(16-81-49)40(69)53-19(3)39(52)68/h5-9,12-16,20,25,31,33,36,54,65-67H,3,10-11,17H2,1-2,4H3,(H2,52,68)(H,53,69)(H,55,73)(H,56,70)(H,57,71)(H,64,72)/b23-5- |
| SMILES | C/C=C1/c2nc(cs2)C(=O)NC3CC(C(=O)OCc4cccc5c4c(c([nH]5)C(=O)SCC(c6nc(cs6)-c7c(cc(c(n7)c8nc(cs8)C(=O)NC(=C)C(=O)N)O)-c9nc(cs9)C(=O)NC(C(=O)N1)C(C)O)NC(=O)c1csc3n1)C)O |
