AG Scientific/NHI-2 | LDHA inhibitor/N-2751/10 mg
商品编号：
N-2751-10mg
品牌：
agscientific
市场价：
¥1900.00
美元价：
1425.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
NHI-2 (1269802-97-2) is a selective inhibitor of Lactate Dehydrogenase A (LDHA) - IC50 in vitro = 14.7 μM (NADH), 10.5 μM (Pyruvate). NHI-2 has also shown cellular growth inhibitory effects against pancreatic cancer cells (PANC-1 cells IC50 = 22.2 μM normoxic and 4.0 μM hypoxic; LPC006 cells IC50 = 17.8 μM normoxic and 1.1 μM hypoxic) with increased efficacy in a cancer cells hypoxic environment. LDHA is a key enzyme involved in the Warburg effect and a cancer cells ability to survive in a hypoxic environment.
Additional Information
| Product # | N-2751 |
|---|---|
| CAS # | 1269802-97-2 |
| Formula | C17H12F3NO3 |
| MW | 335.28 |
| Appearance | Off-white solid |
| Purity | 98% by HPLC NMR (Confirms) |
| Solubility | Soluble in DMSO (up to 25 mg/ml). |
| Storage Temp | -20° |
Additional Information
品牌介绍
AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。
