AG Scientific/MF-438, SCD1 inhibitor/M-3329/25 mg
商品编号：
M-3329-25mg
品牌：
agscientific
市场价：
¥5000.00
美元价：
3750.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MF-438 (921605-87-0) is a potent inhibitor of stearoyl-CoA desaturase 1 (SCD1) - IC50= 2.3 nM. MF-438 was potent in an in vivo mouse liver PD assay (ED50 between 1 and mg/kg). Cancer initiating cells (CSC-like) were shown to much more sensitive to MF-438 inhibition of SCD1 than progenitor and terminally differentiated cancer cells in a lung cancer model. MF-438 showed good oral bioavailability and metabolic stability making it an excellent tool for studying the effects of SCD1 in various disease models.
Additional Information
| Product # | M-3329 |
|---|---|
| CAS # | 921605-87-0 |
| Chemical Name | 2-Methyl-5-(6-(4-(2-trifluoromethyl)phenoxy)piperidin-3-yl)-1,3,4-thiadiazole |
| Formula | C19H18F3N5OS |
| MW | 421.44 |
| Appearance | Off-white solid |
| Purity | 98% by HPLC NMR (Confirms) |
| Solubility | Soluble in DMSO (up to 5 mg/ml) or in Ethanol (up to 2 mg/ml with warming). |
| Storage Temp | -20° |
Additional Information
品牌介绍
AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。
