AG Scientific//E-2312/5 mg
商品编号：
E-2312-5mg
品牌：
agscientific
市场价：
¥1707.40
美元价：
1280.55
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
LY294002EZSOLUTIONisa10mM(5mg/1627µl)solutionofPI-3Kinaseinhibitor
LY-294002EZSOLUTIONisacell-permeable,potentandspecificphosphatidylinositol3-kinase(PI3-kinase)inhibitorthatactsontheATP-bindingsiteoftheenzyme(IC50=1.4µM).AlsoinhibitsnonhomologousDNAend-joining(NHED)inthe460kDaphosphatidylinositol3-likekinaseDNA-PKcs,whichisthecatalyticsubunitofDNA-activatedproteinkinase.
LY-294002doesnotaffecttheactivityofEGFreceptorkinase,MAPkinase,PKC,PI4-kinase,S6kinase,andc-srcat50µM.Blockstheproliferationofculturedrabbitaorticsmoothmusclecellswithoutinducingapoptosis.ReportedtoinhibithistaminesecretioninRBL-2H3cells(IC50=5µM).
AdditionalInformation
| Synonyms | LY-294002Solution |
|---|---|
| Product# | E-2312 |
| CAS# | 154447-36-6 |
| ChemicalName | 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |
| Formula | C19H17NO3 |
| MW | 307.34 |
| Appearance | Liquid |
| Purity | ≥98%byHPLC |
| StorageTemp | -20°C |
