AG Scientific/Kijanimicin/K-2025/2.5 mg
商品编号：
K-2025-2.5mg
品牌：
agscientific
市场价：
¥23305.20
美元价：
13983.12
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
*PleaseinquiretheavailABIlityforthisproduct.Kijanimicinisatetronicacidrelatedtosaccharocarcin,chlorothricin,versipelostatinandtetrocarcin.Likethetetrocarcins,kijanimicincontainsanunusualnitroaminoglycoside.Kijanimicinisapotentantibacterial,antimalarialandantitumoractive.Severalmembersofthisclasshavereceivedconsiderableliteraturefocus.VersipelostatininhibitstranscriptionfromthepromoterofGRP78,agenethatisactivatedaspartofastresssignallingpathwayunderglucosedeprivationresultinginunfoldedproteinresponse(UPR).TheUPR-inhibitoryactionisseenonlyinconditionsofglucosedeprivationandcausesselectiveandmassivekillingoftheglucose-deprivedcells.TetrocarcinAappearstotargetthephosphatidylinositide-3"-kinase/Aktsignallingpathway.
AdditionalInformation
| Synonyms | Sch25663 |
|---|---|
| Product# | K-2025 |
| CAS# | 78798-08-0 |
| Formula | C67H100N2O24 |
| MW | 1317.5 |
| Appearance | Whitesolid |
| Purity | >99%byHPLC |
| Solubility | Solubleinethanol,methanol,DMF,DMSO,andwater(limit) |
| StorageTemp | -20°C |
| TherapeuticArea | InfectiousDiseases |
| Use | Kijanimicinhaspotentantibacterial,antimalarialandantitumoractivity |
| MDLNumber | MFCD01939675 |
|---|---|
| InChI | InChI=1S/C67H100N2O24/c1-29-15-18-45(88-52-27-65(11,69(79)80)60(38(10)87-52)68-64(78)82-14)30(2)20-40-21-39(28-70)33(5)26-67(40)62(76)53(63(77)93-67)61(75)66(12)42(29)17-16-41-54(66)31(3)19-32(4)57(41)91-51-24-46(56(74)35(7)84-51)89-50-25-47(90-48-22-43(71)55(73)34(6)83-48)59(37(9)86-50)92-49-23-44(72)58(81-13)36(8)85-49/h15-17,20-21,31-38,40-52,54-60,70-74,77H,18-19,22-28H2,1-14H3,(H,68,78)/b29-15-,30-20+/t31-,32-,33+,34-,35-,36-,37-,38+,40+,41-,42-,43+,44+,45-,46+,47+,48-,49+,50-,51-,52-,54+,55-,56-,57-,58-,59-,60-,65-,66+,67?/m0/s1 |
| SMILES | C[C@H]1C[C@@H]([C@@H]([C@@H]2[C@@H]1[C@]3([C@@H](C=C2)/C(=CC[C@@H](/C(=C/[C@@H]4C=C([C@@H](CC45C(=O)C(=C(O5)O)C3=O)C)CO)/C)O[C@H]6C[C@]([C@H]([C@H](O6)C)NC(=O)OC)(C)[N+](=O)[O-])/C)C)O[C@H]7C[C@H]([C@H]([C@@H](O7)C)O)O[C@H]8C[C@H]([C@H]([C@@H](O8)C)O[C@@H]9C[C@H]([C@H]([C@@H](O9)C)OC)O)O[C@H]1C[C@H]([C@H]([C@@H](O1)C)O)O)C |
