*PleaseinquiretheavailABIlityforthisproduct.IvermectinB1b(dihydroavermectinB1b)istheminorcomponent(<20%) of="" the="" commercial="" anthelmintic,="" ivermectin.="" members="" of="" the="" avermectin/milbemycin="" anthelmintic="" class="" exert="" their="" anthelmintic="" effects="" by="" binding="" to="" glutamate-gated="" chloride="" channels="" expressed="" on="" nematode="" neurones="" and="" pharyngeal="" muscle="" cells.="" the="" avermectin/milbemycins="" are="" also="" potent="" insecticides.="" in="" vitro,="" the="" b1b="" (25-iso-propyl)="" analogue="" is="" slightly="" more="" potent="" than="" the="" 25-sec-butyl="" (b1a)="" analogue="" as="" an="" inhibitor="" of="" nematode="" larval="" development="" and="" paralysis,="" and="" also="" a="" more="" sensitive="" probe="" for="" ivermectin="" resistance.="">

AdditionalInformation

AdditionalInformation

Synonyms	DihydroavermectinB1b,22,23-DihydroavermectinB1b
Product#	I-2583
CAS#	70209-81-3
Formula	C47H72O14
MW	861.1
Appearance	Whitesolid
Purity	>95%byHPLC
Solubility	Solubleinethanol,methanol,DMSO,andDMFInsolubleinwater
BoilingPoint	934.12°Cat760mmHg
StorageTemp	-20°C
TherapeuticArea	InfectiousDiseases
Use	IvermectinB1b(dihydroavermectinB1b)istheminorcomponentofthecommercialanthelmintic

MDLNumber	MFCD14635434
InChI	InChI=1S/C47H72O14/c1-24(2)41-27(5)16-17-46(61-41)22-33-19-32(60-46)15-14-26(4)42(25(3)12-11-13-31-23-54-44-39(48)28(6)18-34(45(50)57-33)47(31,44)51)58-38-21-36(53-10)43(30(8)56-38)59-37-20-35(52-9)40(49)29(7)55-37/h11-14,18,24-25,27,29-30,32-44,48-49,51H,15-17,19-23H2,1-10H3/b12-11+,26-14+,31-13+/t25-,27-,29-,30-,32+,33-,34-,35-,36-,37-,38-,39+,40-,41+,42-,43-,44+,46+,47+/m0/s1
SMILES	C[C@H]1CC[C@]2(C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)C)O[C@@H]1C(C)C