AG Scientific/Leucinostatin A/L-2539/0.5 mg
商品编号：
L-2539-0.5mg
品牌：
agscientific
市场价：
¥3619.00
美元价：
2714.25
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
*PleaseinquiretheavailABIlityforthisproduct.LeucinostatinAisthemajorcomponentofanatypicalnonapeptidecomplexproducedbyPaecilomyceslilacinus,firstreportedin1973.LeucinostatinsdisplaybroadbioactivityagainstGrampositivebacteria,fungi,plantsandtumorcelllines.LeucinostatinAinhibitsrespirationbyuncouplingoxidativephosphorylationandispotentiatedbyinhibitorssuchasventuricidinandoligomycin.Morerecently,interestinleucinostatinhasfocusedonunderstandingitsactivityasaninsulin-likegrowthfactorIregulator,anionophore,inhibitorofcellsurfaceexpressionofviralglycoproteinsanditsanti-trypanosomalactivity.
AdditionalInformation
| Synonyms | Tryanocidin,CC1014,M13959,ML1014,P168,SF1907VIII,U53496 |
|---|---|
| Product# | L-2539 |
| CAS# | 76600-38-9 |
| Formula | C62H111N11O13 |
| MW | 1218.6 |
| Appearance | Lighttantotansolid |
| Purity | >95%byHPLC |
| Solubility | Solubleinethanol,methanol,DMF,DMSO,andwater(limitedly) |
| BoilingPoint | 1408.0±65.0°Cat760mmHg |
| StorageTemp | -20°C |
| TherapeuticArea | OncologicalDisorders |
| Use | LeucinostatinAinhibitsprostatecancergrowththroughreductionofinsulin-likegrowthfactor-Iexpressioninprostatestromalcells |
| InChI | InChI=1S/C62H111N11O13/c1-21-38(9)23-24-49(77)73-33-40(11)31-47(73)55(82)66-46(30-39(10)29-43(75)32-42(74)22-2)53(80)68-50(51(78)37(7)8)56(83)70-61(15,16)58(85)67-44(27-35(3)4)52(79)65-45(28-36(5)6)54(81)69-62(17,18)59(86)71-60(13,14)57(84)63-26-25-48(76)64-41(12)34-72(19)20/h43-24,35-41,43-47,50-51,75,78H,21-22,25-34H2,1-20H3,(H,63,84)(H,64,76)(H,65,79)(H,66,82)(H,67,85)(H,68,80)(H,69,81)(H,70,83)(H,71,86)/b24-23+ |
|---|---|
| SMILES | CCC(C)/C=C/C(=O)N1CC(CC1C(=O)NC(CC(C)CC(CC(=O)CC)O)C(=O)NC(C(C(C)C)O)C(=O)NC(C)(C)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(C)(C)C(=O)NC(C)(C)C(=O)NCCC(=O)NC(C)CN(C)C)C |
