AG Scientific/Hygrolidin/H-2485/5毫克
商品编号：
H-2485-5mg
品牌：
agscientific
市场价：
¥23920.40
美元价：
14352.24
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
*PleaseinquiretheavailABIlityforthisproduct.Hygrolidinisa16-memberedmacrocycliclactonecloselyrelatedtothebafilomycins,activeagainstValsaceratosperma,thepathogenofapplecankerdisease.HygrolidinisactiveagainstSV40tumorcells,andinhibitsthegrowthofsolidtumor-derivedcelllinessuchasDLD-1humancoloncancercellswithincreasedcellsinG1andSphases.Hygrolidindecreasescyclin-dependentkinase(cdk)4,cyclinDandcyclinB,andincreasescyclinEandp21levels.Hygrolidin-inducedp21inhibitscyclinA-cdk2complexmorestronglythancyclinE-cdk2complex.Italsoincreasesp21mRNAinDLD-1cells,butnotinnormalfibroblasts.
AdditionalInformation
| Product# | H-2485 |
|---|---|
| CAS# | 83329-73-1 |
| Formula | C38H58O11 |
| MW | 690.9 |
| Appearance | Whitesolid |
| Purity | >95%byHPLC |
| Solubility | Solubleinethanol,methanol,DMSO,DMF,andwater(Limited) |
| BoilingPoint | 813.6±65.0°Cat760mmHg |
| StorageTemp | -20°C |
| TherapeuticArea | OncologicalDisorders |
| Use | HygrolidinisactiveagainstSV40tumourcells,andinhibitsthegrowthofsolidtumour-derivedcelllinessuchasDLD-1humancoloncancercellswithincreasedcellsinG1andSphases |
| MDLNumber | MFCD16876182 |
|---|---|
| InChI | InChI=1S/C37H56O11/c1-20-12-11-13-29(45-10)35(47-36(43)24(5)18-21(2)17-23(4)33(41)22(3)16-20)26(7)34(42)27(8)37(44)19-30(25(6)28(9)48-37)46-32(40)15-14-31(38)39/h11-15,17-18,22-23,25-30,33-35,41-42,44H,16,19H2,1-10H3,(H,38,39)/b13-11+,15-14+,20-12+,21-17+,24-18+/t22-,23+,25-,26-,27-,28+,29-,30+,33-,34+,35+,37+/m0/s1 |
| SMILES | CO[C@H]1C=CC=C(C)C[C@H](C)[C@H](O)[C@H](C)C=C(/C)C=C(C)C(=O)O[C@@H]1[C@@H](C)[C@@H](O)[C@H](C)[C@@]1(O)C[C@@H](OC(=O)C=CC(O)=O)[C@@H](C)[C@@H](C)O1C[C@H]1C/C(=C/C=C/[C@@H]([C@H](OC(=O)/C(=C/C(=C/[C@H]([C@H]1O)C)/C)/C)[C@@H](C)[C@H]([C@H](C)[C@]2(C[C@H]([C@H]([C@H](O2)C)C)OC(=O)/C=C/C(=O)O)O)O)OC)/C |
