AG Scientific/GSK-J1, JMJ H3K27 Demethylase inhibitor (Non-cell permeable)/G-2641/25 mg
商品编号：
G-2641-25mg
品牌：
agscientific
市场价：
¥6000.00
美元价：
3600.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
GSK-J1 (1373422-53-7) is a potent and selective inhibitor of jumonji H3K27 histone demethylases JMJD3 and UTX (IC50 = 60 nM, human JMJD3). This is the first known inhibitor selective for the H3K27me3-specific JMJ subfamily which binds to the active catalytic site of the enzyme. The COOH group confers cell impermeability and as such GSK-J1 is useful as a standard in in vitro assays. A cell permeable ethyl ester analog is also available, see GSK-J4 (cat.# 10-1394).
Additional Information
| Product # | G-2641 |
|---|---|
| CAS # | 1373422-53-7 |
| Chemical Name | N-[2-(2-Pyridinyl)-6-(1,2,4,5-tetrahydro-3H-3-benzazepin-3-yl)-4-pyrimidinyl]-β-alanine |
| Formula | C22H23N5O2 |
| MW | 389.46 |
| Appearance | Pale yellow solid |
| Purity | 99% by TLC NMR (Conforms) |
| Solubility | Soluble in DMSO (up to 20 mg/ml). |
| Storage Temp | RT (des.) |
Additional Information
品牌介绍
AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。
