AG Scientific/EZSolution CHIR99021/E-2311/5 mg
商品编号：
E-2311-5mg
品牌：
agscientific
市场价：
¥3734.80
美元价：
2801.10
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
CHIR99021 is an aminopyrimidine derivative that inhibits GSK3α and GSK3β. It activates glycogen synthesis in CHO-IR cells and in isolated type 1 diabetic rat skeletal muscle and it has also been shown to induce the reprogramming of murine and human somatic cells into stem cells
Additional Information
| Synonyms | 6-((2-((4-(2,4-Dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile; CT99021 |
|---|---|
| Product # | E-2311 |
| CAS # | 252917-06-9 |
| Chemical Name | 6-((2-((4-(2,4-Dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile; CT99021 |
| Formula | C22H18Cl2N8 |
| MW | 465.34 |
| Appearance | Liquid |
| Purity | 98% by HPLC |
| Melting Point | 316.33 °C |
| Storage Temp | -20°C |
| Therapeutic Area | Endocrinological Disorders |
| Use | CHIR99021 is GSK3β kinase inhibitor enhances glucose metabolism in type 2 diabetes |
Additional Information
| MDL Number | MFCD11846251 |
|---|---|
| ChemACX | X1755647-3 |
| InChI | InChI=1S/C22H18Cl2N8/c1-13-10-29-21(31-13)17-12-30-22(32-20(17)16-4-3-15(23)8-18(16)24)27-7-6-26-19-5-2-14(9-25)11-28-19/h4-5,8,10-12H,6-7H2,1H3,(H,26,28)(H,29,31)(H,27,30,32) |
| SMILES | CC1=CNC(=N1)C2=CN=C(N=C2C3=C(C=C(C=C3)Cl)Cl)NCCNC4=NC=C(C=C4)C#N |
品牌介绍
AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。
