AG Scientific/Epothilone B/E-2449/0.1 mg
商品编号:
E-2449-0.1mg
品牌:
agscientific
市场价:
¥6402.60
美元价:
3841.56
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
*Please inquire the availability for this product. Epothilone B is a microtubule inhibitor isolated from the myxobacteria, Sorangium cellulosum. Like epothilone A, epothilone B acts by stabilising microtubule formation at the taxol binding site, and causes cell cycle arrest at the G2/M transition, leading to cytotoxicity.
Additional Information
Synonyms | EpoB |
---|---|
Product # | E-2449 |
CAS # | 152044-54-7 |
Formula | C27H4NO6S |
MW | 507.7 |
Appearance | White to off white powder |
Purity | >98% by HPLC |
Solubility | Soluble in Chloroform, Dichloromethane, DMSO, Ethanol and Methanol |
Melting Point | 95-97°C |
Boiling Point | 95-97°C |
Storage Temp | -20°C |
Therapeutic Area | Oncological Disorders |
Use | Epo B causes cell cycle arrest in cell lines from ovarian, breast, lung, colon, prostate, and squamous cancer. |
Additional Information
MDL Number | MFCD02101921 |
---|---|
InChI | InChI=1S/C27H41NO6S/c1-15-9-8-10-27(7)22(34-27)12-20(16(2)11-19-14-35-18(4)28-19)33-23(30)13-21(29)26(5,6)25(32)17(3)24(15)31/h11,14-15,17,20-22,24,29,31H,8-10,12-13H2,1-7H3/b16-11+/t15-,17+,20-,21-,22-,24-,27+/m0/s1 |
SMILES | Cc1nc(cs1)/C=C(C)/[C@@H]2C[C@H]3[C@](O3)(CCC[C@@H]([C@@H]([C@H](C(=O)C([C@H](CC(=O)O2)O)(C)C)C)O)C)C |
品牌介绍
AG Scientific, Inc.成立于1997年,专注于创新生化制剂以及用于诊断测试开发的定制原材料,以推进临床前研究药物开发。产品涉及抗生素,生物洗涤剂,缓冲液,诊断,酶,医疗设备试剂,蛋白酶K,还原剂,RNase A等。