AG Scientific/Gilvocarcin V/G-2519/25 mg
商品编号：
G-2519-25mg
品牌：
agscientific
市场价：
¥18508.60
美元价：
11105.16
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
*Please inquire the availability for this product. Gilvocarcin V is the major analogue of a complex of C-glycoside antitumor actives isolated from a Streptomyces sp.. Gilvocarcin V contains a vinyl group in the 8-position, and is the most potent analogue of the complex. It is thought to act as an inhibitor of the catalytic activity of human topoisomerase II. The metabolite displays potent antibacterial, antifungal, antiviral and antitumor activity. Recent research suggests that the gilvocarcins act as photoactivated cross-linkers of DNA to histones.
Additional Information
| Synonyms | Anandimycin A, Toromycin, 1072B |
|---|---|
| Product # | G-2519 |
| CAS # | 77879-90-4 |
| Formula | C27H26O9 |
| MW | 494.5 |
| Appearance | Yellow crystals |
| Purity | >95% by HPLC |
| Solubility | Soluble in DMSO, DMF (moderately), methanol (moderately), ethanol (moderately), and water (poor) |
| Melting Point | 322.54 °C |
| Boiling Point | 821.61 °C at 760 mmHg |
| Storage Temp | -20°C |
| Therapeutic Area | Oncological Disorders |
| Use | A metabolite that displays potent antibacterial, antifungal and antiviral activity |
Additional Information
| MDL Number | MFCD01939442 |
|---|---|
| InChI | InChI=1S/C27H26O9/c1-5-12-8-15-19(17(9-12)33-3)14-10-18(34-4)21-16(29)7-6-13(20(21)25(14)36-27(15)32)26-23(31)22(30)24(35-26)11(2)28/h5-11,22-24,26,28-31H,1H2,2-4H3/t11?,22?,23?,24?,26-/m1/s1 |
| SMILES | CC(C1C(C([C@H](O1)c2ccc(c3c2c4c(cc3OC)c5c(cc(cc5OC)C=C)c(=O)o4)O)O)O)O |
品牌介绍
AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。
