AG Scientific/FSG67, GPAT inhibitor/F-2489/50 mg
商品编号：
F-2489-50mg
品牌：
agscientific
市场价：
¥3900.00
美元价：
2925.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
FSG67 (1158383-34-6) is an inhibitor of Glycerol 3-Phosphate Acyltransferase (GPAT); IC50 = 24 μM. It was able to reduce food intake, decrease body weight and adiposity, enhance energy utilization as fatty acid oxidation, reverse hepatic steatosis, and enhance insulin sensitivity in diet-induced obese mice while showing no in vitro or in vivo toxicity. FSG67 also caused decreased gene expression for orexigenic hypothalamic neuropeptides AgRP and NPY. FSG67 increased FAOx in primary hypothalamic neurons (PHN) leading to an increase in ATP and inactivation of AMPK. Oxidative stress and indicators of ER stress were also reduced in PHN.
Additional Information
| Product # | F-2489 |
|---|---|
| CAS # | 1158383-34-6 |
| Chemical Name | 2-(Nonylsulfonamido)benzoic acid |
| Formula | C16H25NO4S |
| MW | 327.44 |
| Appearance | White solid |
| Purity | 98% by TLC NMR (Conforms) |
| Solubility | Soluble in DMSO (greater than 25 mg/ml) or in Ethanol (greater than 25 mg/ml) |
| Storage Temp | RT (des.) |
Additional Information
品牌介绍
AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。
