AG Scientific/Fidaxomicin/F-2425/5 mg
商品编号：
F-2425-5mg
品牌：
agscientific
市场价：
¥22408.80
美元价：
13445.28
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
*PleaseinquiretheavailABIlityforthisproduct.Fidaxomicinisarecentlymarketedantibioticwithaconfusinghistorydatingbacktoitsoriginalisolationin1975.Fidaxomicinisthemajoranalogueofafamilyofmacrocycliclactones,isolatedindependentlybythreedifferentgroupsfromculturesbelongingtothreedifferentgenera(Actinoplanes,DactylosporangiumandMicromonospora)knownaslipiarmycinA3,tiacumicinBandclostomicinB1,respectively.FidaxomicinisanarrowspectrumantibioticwithexcellentactivityagainstGrampositivebacteria,notablyClostridiumdifficile.FidaxomicinactsinthegastrointestinaltractwithoutunduedisruptiontogutmicroMSTlflora.
AdditionalInformation
| Synonyms | ClostomicinB1,LipiarmycinA3,TiacumicinB,OPT80 |
|---|---|
| Product# | F-2425 |
| CAS# | 873857-62-6 |
| Formula | C52H74Cl2O18 |
| MW | 1058 |
| Appearance | Whitesolid |
| Purity | >98%byHPLC |
| Solubility | Solubleinethanol,methanol,DMF,DMSO,andLimitedwatersolubility |
| BoilingPoint | 1046.4±65.0°Cat760mmHg |
| StorageTemp | -20°C |
| TherapeuticArea | InfectiousDiseases |
| Use | Fidaxomicinisanarrowspectrumantibiotic,inhibitingbacterialRNApolymeraseanddemonstratesexcellentactivityagainstGrampositivebacteria |
| MDLNumber | MFCD27976367 |
|---|---|
| InChI | InChI=1S/C52H74Cl2O18/c1-13-30-22-26(6)33(56)18-16-15-17-31(23-66-51-45(65-12)42(61)44(29(9)67-51)69-49(64)35-32(14-2)36(53)39(58)37(54)38(35)57)48(63)68-34(28(8)55)20-19-25(5)21-27(7)43(30)70-50-41(60)40(59)46(52(10,11)72-50)71-47(62)24(3)4/h15-17,19,21-22,24,28-30,33-34,40-46,50-51,55-61H,13-14,18,20,23H2,1-12H3/b16-15+,25-19+,26-22+,27-21+,31-17+/t28-,29-,30+,33+,34+,40-,41+,42+,43+,44-,45+,46+,50-,51-/m1/s1 |
| SMILES | CC[C@H]1/C=C(/[C@H](C/C=C/C=C(/C(=O)O[C@@H](C/C=C(/C=C(/[C@@H]1O[C@H]2[C@H]([C@H]([C@@H](C(O2)(C)C)OC(=O)C(C)C)O)O)C)C)[C@@H](C)O)CO[C@H]3[C@H]([C@H]([C@@H]([C@H](O3)C)OC(=O)C4=C(C(=C(C(=C4O)Cl)O)Cl)CC)O)OC)O)C |
