AG Scientific/EZSolution SB-431542/E-2320/1 mg
商品编号：
E-2320-1mg
品牌：
agscientific
市场价：
¥1707.40
美元价：
1280.55
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
SB-431542 is a potent and selective inhibitor of TGF-β superfamily type I activin receptor-like kinase (ALK) receptors, specifically ALK4, ALK5 and ALK7. Inhibition of TGF-β signaling is known to induce the de-repression of epithelial fate and thus was hypothesized to benefit the reprogramming process.
Additional Information
| Synonyms | 4-[4-(1,3-benzodioxol-5-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamide |
|---|---|
| Product # | E-2320 |
| CAS # | 301836-41-9 |
| Chemical Name | 4-[4-(1,3-benzodioxol-5-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamide |
| Formula | C22H18N4O3 |
| MW | 384.39 |
| Appearance | Liquid |
| Purity | 98% |
| Melting Point | 315.72 °C |
| Boiling Point | 662.4±55.0 °C at 760 mmHg |
| Storage Temp | -20°C |
| Therapeutic Area | Oncological Disorders |
| Use | A specific and selective inhibitor of TGF-ß type I ALK receptors and Smad3.It also suppressed the TGF-beta-induced proliferation of osteosarcoma |
Additional Information
| MDL Number | MFCD05865244 |
|---|---|
| ChemACX | X1430393-8 |
| InChI | InChI=1S/C22H16N4O3/c23-21(27)13-4-6-14(7-5-13)22-25-19(20(26-22)16-3-1-2-10-24-16)15-8-9-17-18(11-15)29-12-28-17/h1-11H,12H2,(H2,23,27)(H,25,26) |
| SMILES | c1ccnc(c1)c2c(nc([nH]2)c3ccc(cc3)C(=O)N)c4ccc5c(c4)OCO5 |
品牌介绍
AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。
