AG Scientific/Doramectin/D-2529/25 mg
商品编号:
D-2529-25mg
品牌:
agscientific
市场价:
¥9689.20
美元价:
5813.52
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
*PleaseinquiretheavailABIlityforthisproduct.DoramectinisabiosyntheticavermectinderivedfromamutantstrainofStreptomycesavermitilis,supplementedwithacyclohexylcaboxylicacidstartingunit.Doramectinwasdevelopedasananthelminticforinternalparasitecontrol.Thepresenceofthecyclohexylgroupreplacingthesec-butylmoietyaffordsgreaterhydrophobicityandlongerBIOLOGicalhalf-lifecomparedtoavermectin.Liketheothermilbemycin/avermectins,itselectivelybindstoparasiteglutamate-gatedchlorideionchannelsanddisruptsneurotransmissionleADIngtoparalysisanddeathoftheparasite.
AdditionalInformation
Synonyms | Dectomax |
---|---|
Product# | D-2529 |
CAS# | 117704-25-3 |
Formula | C50H74O14 |
MW | 899.1 |
Appearance | Whitesolid |
Purity | >99%byHPLC |
Solubility | Solubleinwater(partly),chloroform,andmethanol |
MeltingPoint | 168°C |
BoilingPoint | 967.4°Cat760mmHg |
StorageTemp | -20°C |
Use | Doramectinisaveterinarydrugforthetreatmentofparasitessuchasgastrointestinalroundworms,lungworms,eyeworms |
MDLNumber | MFCD00894747 |
---|---|
InChI | InChI=1S/C50H74O14/c1-27-13-12-16-34-26-57-47-42(51)30(4)21-37(50(34,47)54)48(53)60-36-22-35(63-49(25-36)20-19-29(3)45(64-49)33-14-10-9-11-15-33)18-17-28(2)44(27)61-41-24-39(56-8)46(32(6)59-41)62-40-23-38(55-7)43(52)31(5)58-40/h12-13,16-17,19-21,27,29,31-33,35-47,51-52,54H,9-11,14-15,18,22-26H2,1-8H3/b13-12+,28-17+,34-16+/t27-,29-,31-,32-,35+,36-,37-,38-,39-,40-,41-,42+,43-,44-,45-,46-,47+,49+,50+/m0/s1 |
SMILES | C[C@H]1/C=C/C=C/2CO[C@H]3[C@@]2([C@@H](C=C([C@H]3O)C)C(=O)O[C@H]4C[C@@H](C/C=C(/[C@H]1O[C@H]5C[C@@H]([C@H]([C@@H](O5)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O)OC)OC)C)O[C@]7(C4)C=C[C@@H]([C@H](O7)C8CCCCC8)C)O |