AG Scientific/肉桂霉素/C-2639/1 mg
商品编号：
C-2639-1mg
品牌：
agscientific
市场价：
¥5378.00
美元价：
3226.80
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
*PleaseinquiretheavailABIlityforthisproduct.Cinnamycin(lanthiopeptin)isahighmolecularweighttricyclicantibioticproducedbyseveralspeciesofStreptoverticillium.CinnamycinisapotentindirectinhibitorofphospholipaseA2,actingbyspecificallysequesteringphosphatidylethanolamine(PE),amajorcomponentofthemammalianplasmacellmembrane.Cinnamycininducestrans-bilayerphospholipidmovementincellmembranestoexposeinternallyboundPE.AthighsurfaceconcentrationsofPE,cinnamycininducesmembranereorganisationincludingmembranefusionandalterationofgrossmorphology.
AdditionalInformation
| Synonyms | Lanthiopeptin,Ro09-0198 |
|---|---|
| Product# | C-2639 |
| CAS# | 110655-58-8 |
| Formula | C89H125N25O25S3 |
| MW | 2041.3 |
| Appearance | Whitetooffwhitesolid |
| Purity | >98%byHPLC |
| Solubility | SolubleinDMSO(10mg/ml),DMF,methanol,ethanol,andwater(poorly) |
| StorageTemp | -20°C |
| TherapeuticArea | InfectiousDiseases |
| Use | Cinnamycinisatetracyclicpolypeptideantibiotic |
| MDLNumber | MFCD01770867 |
|---|---|
| InChI | InChI=1S/C89H125N25O25S3/c1-43(2)66-84(133)109-59-41-140-40-58-79(128)108-60-42-142-45(4)68(86(135)105-55(75(124)110-66)34-48-22-12-7-13-23-48)111-76(125)54(33-47-20-10-6-11-21-47)104-82(131)61-26-17-31-114(61)65(118)38-98-72(121)53(32-46-18-8-5-9-19-46)103-78(127)57(106-80(60)129)36-95-29-15-14-24-52(87(136)137)102-85(134)67(112-77(126)56(35-63(92)116)99-64(117)37-97-83(132)69(113-81(59)130)70(119)88(138)139)44(3)141-39-49(90)71(120)100-50(25-16-30-96-89(93)94)73(122)101-51(74(123)107-58)27-28-62(91)115/h5-13,18-23,43-45,49-61,66-70,95,119H,14-17,24-42,90H2,1-4H3,(H2,91,115)(H2,92,116)(H,97,132)(H,98,121)(H,99,117)(H,100,120)(H,101,122)(H,102,134)(H,103,127)(H,104,131)(H,105,135)(H,106,129)(H,107,123)(H,108,128)(H,109,133)(H,110,124)(H,111,125)(H,112,126)(H,113,130)(H,136,137)(H,138,139)(H4,93,94,96)/t44-,45?,49+,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,66+,67?,68+,69+,70-/m1/s1 |
| SMILES | C[C@@H]1C2C(=O)N[C@@H](CCCCNC[C@H]3C(=O)N[C@H](C(=O)NCC(=O)N4CCC[C@H]4C(=O)N[C@H](C(=O)N[C@H]5C(SC[C@@H](C(=O)N3)NC(=O)[C@H](CSC[C@@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N2)CC(=O)N)[C@H](C(=O)O)O)NC(=O)[C@@H](NC(=O)[C@@H](NC5=O)CC6=CC=CC=C6)C(C)C)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CS1)N)CCCNC(=N)N)CCC(=O)N)C)CC7=CC=CC=C7)CC8=CC=CC=C8)C(=O)O |
