AG Scientific/Pepstatin A/P-1519-
商品编号：
P-1519-
品牌：
agscientific
市场价：
¥500.00
美元价：
375.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
More Information
Alternate Name/Synonyms
Pepstatin; Isoval-Val-Val-Sta-Ala-Sta; Pepsin Inhibitor S 735A; NSC 272671
SKU
P-1519
CAS #
26305-03-3
Chemical Name
(3S,4S)-3-hydroxy-4-[[(2S)-2-[[(3S,4S)-3-hydroxy-6-methyl-4-[[(2S)-3-methyl-2-[[(2S)-3-methyl-2-(3-methylbutanoylamino)butanoyl]amino]butanoyl]amino]heptanoyl]amino]propanoyl]amino]-6-methylheptanoic acid
Chemical Formula
C34H63N5O9
Molecular Weight
685.91 Da
Appearance
White powder
Purity
≥98% (HPLC)
Solubility
DMSO (5 mg/mL) or methanol (1 mg/mL)
Storage Temp
-20°C, desiccated
THERAPEUTIC AREA
Not Available
USE
Pepstatin A is a potent reversible inhibitor of aspartic proteases. It inhibits the aspartic proteases cathepsin D, pepsin, and renin. Additionally, it suppresses p53-dependent apoptosis in lymphoid cells as well as TNFα-induced apoptosis in U937 cells. Pepstatin A also efficiently inhibits HIV-1 protease and Fcγ receptor induction by IFN-γ.
MDL NUMBER
MFCD00060740
CHEMACX
X1036275-1
PubChecm ID
5478883
INCHI
InChI=1S/C34H63N5O9/c1-17(2)12-23(37-33(47)31(21(9)10)39-34(48)30(20(7)8)38-27(42)14-19(5)6)25(40)15-28(43)35-22(11)32(46)36-24(13-18(3)4)26(41)16-29(44)45/h17-26,30-31,40-41H,12-16H2,1-11H3,(H,35,43)(H,36,46)(H,37,47)(H,38,42)(H,39,48)(H,44,45)/t22-,23-,24-,25-,26-,30-,31-/m0/s1
SMILES
C[C@@H](C(=O)N[C@@H](CC(C)C)[C@H](CC(=O)O)O)NC(=O)C[C@@H]([C@H](CC(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC(=O)CC(C)C)O
Peptide sequence
ISOVALERYL-VAL-VAL-STA-ALA-STA-OH
RTECS
SC6155000
Handling
Use only in area provided with appropriate exhaust ventilation. Keep away from heat and source of ignition. Empty containers pose a fire risk, evaporate residue under fume hood. Ground all equipment containing material. Do not breathe dust.
msds 1
P-1519 Pepstatin A, SDS, diamond format.pdf
Certificate of Analysis 1
P-1519, J1193.pdf
Certificate of Analysis 2
P-1519, J1077.pdf
Certificate of Analysis 3
P-1519, H1299A.pdf
品牌介绍
AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。
