AG Scientific/P32/98, DPP IV Inhibitor (CD26)/P-1685-
商品编号：
P-1685-
品牌：
agscientific
市场价：
¥200.00
美元价：
150.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
More Information
Alternate Name/Synonyms
Isoleucyl thiazolidide
SKU
P-1685
CAS #
136259-20-6
Chemical Name
(2S, 3S)-2-Amino-3 –methyl-1-(thiazolidin-3-yl)pentan-1-one hemi-fumarate
Chemical Formula
C9H18N2OS • 0.5C4H404
Molecular Weight
260.4 Da
Appearance
White powder
Purity
>98% (TLC)
Solubility
May be dissolved in H2O (20 mg/mL) or DMSO (25 mg/mL).
Melting Point
N/A
Preparation
N/A
Storage Temp
Store desiccated at -20°C
THERAPEUTIC AREA
Endocrine Disorders
USE
P32/98 is a specific, competitive transition-state substrate analog inhibitor of dipeptidyl peptidase IV (DPIV, DPPIV, and CD26). In obese Zucker and lean rats the inhibition of CD26's ability to hydrolyze Glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide (GLP-1) lead to an increased secretion of insulin, especially in the obsese Rat, making P32/98 an important tool in diabetic research. P32/98 has also been shown to augment YY1-36's ability to enhance renovascular responses to angiotensin II in spontaneoulsy hypertensive rats. Due to CD26's effect on upregultating lymphocyte proliferation P32/98 has been demonstrated to decrease the lymphocyte proliferation.
Merck Index
N/A
RTECS
N/A
Handling
Use only in area provided with appropriate exhaust ventilation. Keep away from heat and source of ignition. Empty containers pose a fire risk, evaporate residue under fume hood. Ground all equipment containing material. Do not breathe dust.
msds 1
P-1685, P32-98, SDS, diamond format.pdf
Certificate of Analysis 1
P-1685, J1225A.pdf
Certificate of Analysis 2
P-1685, J1225 (BD).pdf
Certificate of Analysis 3
P-1685, J1160A.pdf
品牌介绍
AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。
