MFCD00214356; Okadaic Acid, Potassium Salt; 9,10-Deepithio-9,10-didehydroacanthifolicin; Halochondrine A

O-1028

155751-72-7

potassium;2-hydroxy-3-[11-hydroxy-2-[4-[4-hydroxy-2-[1-hydroxy-3-(3-methyl-1,7-dioxaspiro[5.5]undecan-2-yl)butyl]-3-methylidenespiro[4a,7,8,8a-tetrahydro-4H-pyrano[3,2-b]pyran-6,5'-oxolane]-2'-yl]but-3-en-2-yl]-4-methyl-1,7-dioxaspiro[5.5]undec-4-en-8-yl]

C₄₄H₆₇O₁₃•K

843.09 Da

White crystalline solid or clear, colorless film

>98%

Soluble in DMSO or ethanol.

164-166°C

N/A

Store desiccated at -20°C. Packaged under argon gas.

Not Available

Okadaic Acid, Potassium Salt is a potent inhibitor of serine/threonine-specific protein phosphatases PP1, PP2A, 5534, PP2C and endogenous phosphatase smooth muscle myosin. This inhibition action has been used to stimulate the activity of glucose transport and has been observed to block insulin's stimulation of glucose transport by inhibiting IRS-1 phosphorylation. Okadaic Acid, Potassium Salt has been used as a response modifier in the study of large granular lymphocyte and T-cell biochemistry. In addition to inhibitive activities it is a tumor promoter and has been used to study nitric oxide metabolism, apoptosis, cell cycle and calcium signaling.

13.6891.2001

MFCD00213389

X1094109-2

InChI=1S/C44H68O13.K/c1-25-21-34(55-44(23-25)35(46)12-11-31(54-44)24-41(6,50)40(48)49)26(2)9-10-30-14-18-43(53-30)19-15-33-39(57-43)36(47)29(5)38(52-33)32(45)22-28(4)37-27(3)13-17-42(56-37)16-7-8-20-51-42;/h9-10,23,26-28,30-39,45-47,50H,5,7-8,11-22,24H2,1-4,6H3,(H,48,49);/q;+1/p-1/b10-9+;/t26-,27-,28+,30+,31+,32+,33-,34+,35-,36-,37+,38+,39-,41-,42+,43-,44-;/m1./s1

C[C@@H]1CC[C@]2(CCCCO2)O[C@@H]1[C@@H](C)C[C@@H]([C@@H]3C(=C)[C@H]([C@H]4[C@H](O3)CC[C@]5(O4)CC[C@@H](O5)/C=C/[C@@H](C)[C@@H]6CC(=C[C@@]7(O6)[C@@H](CC[C@H](O7)C[C@](C)(C(=O)[O-])O)O)C)O)O.[K+]

Not Applicable

UN 2811

II

Not Applicable

Avoid contact with skin and eyes. Avoid formation of dust and aerosols.Further processing of solid materials may result in the formation of combustible dusts. The potential for combustible dust formation should be taken into consideration before additional processing occurs. Provide appropriate exhaust ventilation at places where dust is formed.

O-1028, H1122D.pdf

O-1028, H1122C.pdf

O-1028, H1122B.pdf