AG Scientific/LY-333531/L-1011-
商品编号：
L-1011-
品牌：
agscientific
市场价：
¥20.00
美元价：
15.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
More Information
Alternate Name/Synonyms
Ruboxistaurin, (9S)-9-[(Dimethylamino)methyl]-6,7,10,11-tetrahydro-9H,18H-5,21:12,17-Dimethenodibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20(19H)-dione hydrochloride
SKU
L-1011
CAS #
169939-93-9
Chemical Name
(S)-13-[(Dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16,21-dimetheno-1H, 13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiaza-cyclohexadecene-1,3(2H)-dione. hydrochloride
Chemical Formula
C28H28N4O3.HCl
Molecular Weight
504.5
Appearance
Red to Orange Solid
Purity
98%
Solubility
Soluble in DMSO, Slightly soluble in 100% ethanol or water
Storage Temp
+4°C
THERAPEUTIC AREA
Ophthalmological Disorders
USE
LY333531 is a potent inhibitor of protein kinase Cß use in diabetic. LY333531 improves blood flow and leukocyte entrapment in the retina
MDL NUMBER
MFCD00940226
CHEMACX
X1704593-1
INCHI
InChI=1S/C28H28N4O3.ClH/c1-30(2)15-18-11-12-31-16-21(19-7-3-5-9-23(19)31)25-26(28(34)29-27(25)33)22-17-32(13-14-35-18)24-10-6-4-8-20(22)24;/h3-10,16-18H,11-15H2,1-2H3,(H,29,33,34);1H/t18-;/m0./s1
SMILES
CN(C)C[C@@H]1CCN2C=C(C3=CC=CC=C32)C4=C(C5=CN(CCO1)C6=CC=CC=C65)C(=O)NC4=O.Cl
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Store in Tightly Sealed Vial Protect from Moisture.
Citations
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY:UV-C irradiation disrupts platelet surface disulfide bonds and activates the platelet integrin IIbβ3Robin Verhaar, David W. C. Dekkers, Iris M. De Cuyper, Mark H. Ginsberg, Dirk de Korte, and Arthur J. VerhoevenBlood, Dec 2008; 112: 4935 - 4939.
Citations_Hyperlink
http://bloodjournal.hematologylibrary.org/cgi/reprint/112/13/4935
Certificate of Analysis 1
L-1011_L-1011,_C1215.pdf
Certificate of Analysis 2
L-1011_L-1011,_B1884A.pdf
Certificate of Analysis 3
L-1011_L-1011,_B1884.pdf
品牌介绍
AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。
