AG Scientific/Leupeptin，半硫酸盐/L-1165-
商品编号：
L-1165-
品牌：
agscientific
市场价：
¥200.00
美元价：
150.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
More Information
Alternate Name/Synonyms
Leupeptin hemisulfate salt; Leupeptin hemisulfate anhydrous
SKU
L-1165
CAS #
103476-89-7
Chemical Name
(2S)-2-acetamido-N-[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-methylpentanamide;sulfuric acid
Chemical Formula
C40H78N12O12S
Molecular Weight
951.2 Da
Appearance
White powder
Purity
>90% (HPLC)
Solubility
Soluble in water (50 mg/mL), clear and colorless to faint yellow solution
Melting Point
N/A
Preparation
N/A
Storage Temp
-20°C
THERAPEUTIC AREA
Not Applicable
USE
It is often used during in vitro experiments when a specific enzymatic reaction is being studied. When cells are lysed for these studies, proteases, many of which are contained within lysosomes, are released. These proteases, if freely present in the lysate, would destroy any products from the reaction being studied, and make the experiment uninterpretable. For example, leupeptin could be used in a calpain extraction to keep calpain from being hydrolyzed by specific proteases.
Merck Index
N/A
INCHI
InChI=1S/2C20H38N6O4.H2O4S/c2*1-12(2)9-16(24-14(5)28)19(30)26-17(10-13(3)4)18(29)25-15(11-27)7-6-8-23-20(21)22;1-5(2,3)4/h2*11-13,15-17H,6-10H2,1-5H3,(H,24,28)(H,25,29)(H,26,30)(H4,21,22,23);(H2,1,2,3,4)/t2*15-,16-,17-;/m00./s1
SMILES
OS(O)(=O)=O.[H]C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(C)=O.[H]C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(C)=O
RTECS
N/A
Handling
Avoid contact. Do not get in eyes, on skin, or clothing. Wash thoroughly after handling. Wash contaminated clothing before reuse. Hygroscopic! Protect from light and moisture!
Citations
α-Actinin-4/FSGS1 is required for Arp2/3-dependent actin assembly at the adherens junctionVivian W. Tang and William M. BrieherJ. Cell Biol., Jan 2012; 196: 115 - 130.
Citations_Hyperlink
http://jcb.rupress.org/cgi/reprint/196/1/115
Additional Videos
msds 1
L-1165, Leupeptin, SDS, diamond format.pdf
Certificate of Analysis 1
L-1165, J1181C.pdf
Certificate of Analysis 2
L-1165, J1181B.pdf
Certificate of Analysis 3
L-1165, J1181A.pdf
品牌介绍
AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。
