AG Scientific/Elastatinal，弹性蛋白酶抑制剂/E-2044-
商品编号：
E-2044-
品牌：
agscientific
市场价：
¥500.00
美元价：
375.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
More Information
Alternate Name/Synonyms
(2S)-2-[(4S)-2-Amino-1,4,5,6-tetrahydro4-pyrimidinyl]-N-[[[(1S)-1- carboxy-3-methylbutyl]amino]carbonyl]glycyl-N1-[(1S)-1-methyl-2-ox
SKU
E-2044
CAS #
51798-45-9
Chemical Name
(2S)-2-[(4S)-2-Amino-1,4,5,6-tetrahydro4-pyrimidinyl]-N-[[[(1S)-1-carboxy-3-methylbutyl]amino]carbonyl]glycyl-N1-[(1S)-1-methyl-2-oxoethyl-L-glutamamide
Chemical Formula
C21H36N8O7
Molecular Weight
512.56 Da
Appearance
Yellow to off white powder
Solubility
Soluble in water up to 20 mg/mL. It has been reported to also be soluble in methanol, pyridine, and dimethyl sulfoxide, and slightly soluble in ethanol. Alkaline solutions are unstable.
Melting Point
N/A
Preparation
N/A
Storage Temp
-20°C, desiccated
THERAPEUTIC AREA
Not Applicable
USE
Elastatinal is a protease inhibitor. Studies have demonstrated that Elastatinal can effectively inhibit phenylmethylsulfonyl fluoride (PMSF, sc-3597) degradation of the H1 histone and high mobility group (HMG) proteins. Elastatinal is an elastase inhibitor and has exhibited the ability to inhibit poliovirus and rhinovirus 2A proteinases in vitro. Additionally, it has no effect on DNA repair and UV-induced sister chromatid exchanges, and inhibits the cleavages found at Ala-Ala bonds in peptides that represent the capsid/nucleocapsid site. Elastatinal is an inhibitor of Neutrophil Elastase.
Merck Index
N/A
MDL NUMBER
MFCD00151180
CHEMACX
X1089720-8
PubChecm ID
3211
INCHI
InChI=1S/C21H36N8O7/c1-10(2)8-14(19(34)35)28-21(36)29-16(12-6-7-24-20(23)27-12)18(33)26-13(4-5-15(22)31)17(32)25-11(3)9-30/h9-14,16H,4-8H2,1-3H3,(H2,22,31)(H,25,32)(H,26,33)(H,34,35)(H3,23,24,27)(H2,28,29,36)
SMILES
CC(C)CC(C(=O)O)NC(=O)NC(C1CCN=C(N1)N)C(=O)NC(CCC(=O)N)C(=O)NC(C)C=O
RTECS
LZ9600000
Handling
Keep dry. Freeze upon arrival. Protect from light. Handle in accordance with good industrial hygiene and safety practice.
msds 1
E-2044, Elastatinal SDS, diamond format.pdf
Certificate of Analysis 1
E-2044, J1151.pdf
Certificate of Analysis 2
E-2044, H1430.pdf
Certificate of Analysis 3
E-2044, E1282F.pdf
品牌介绍
AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。
