AG Scientific/丝裂霉素C，在NaCl/M-1130中-
商品编号：
M-1130-
品牌：
agscientific
市场价：
¥40.00
美元价：
30.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
More Information
Alternate Name/Synonyms
Ametycine NaCl, Mitocin C; Mit-C
SKU
M-1130
CAS #
50-07-7
Chemical Name
[(4S,6S,7R,8S)-11-amino-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate
Chemical Formula
C15H18N4O5 • NaCl
Molecular Weight
334.3 Da
Appearance
Blue-violet solid
Purity
≥99% HPLC, TLC
Solubility
Clear blue-violet solution in methanol at 10 mg/mL.
Melting Point
N/A
Preparation
N/A
Storage Temp
4°C
THERAPEUTIC AREA
Oncological Disorders
USE
Mitomycin C, in NaCl is a reagent used to generate mitotically inactive feeder cells in culture. Mitomycin C (4% in NaCl) is a DNA crosslinking agent which inhibits DNA synthesis and causes apoptosis via a p53-dependent pathway. This compound is activated by sodium dithionite which is thought to cause bifunctional alkylation of DNA. In addition, when added to Micrococcus luteus DNA Mitomycin C (4% in NaCl) forms adducts between itself and deoxyguanosine residues.
Merck Index
Merck Index: 13.6236[p.2001
MDL NUMBER
MFCD00078109
CHEMACX
X1004059-0
INCHI
InChI=1S/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15-/m1/s1
SMILES
CC1=C(C(=O)C2=C(C1=O)N3C[C@H]4[C@@H]([C@@]3([C@@H]2COC(=O)N)OC)N4)N
Peptide sequence
Not Applicable
RTECS
CN0700000
UN #'S
UN 2811
PACKING GROUP
II
HAZARD CLASS
Not Applicable
Handling
Use only under a chemical fume hood. Wear personal protective equipment. Do not get in eyes, on skin, or on clothing. Avoid dust formation. Do not breathe vapors/dust. Do not ingest.
Special Shipping
Yes
Certificate of Analysis 1
M-1130, J1300.pdf
Certificate of Analysis 2
M-1130, J1217.pdf
Certificate of Analysis 3
M-1130, F1097.pdf
品牌介绍
AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。
