AG Scientific/Mitomycin C/M-1108-
商品编号：
M-1108-
品牌：
agscientific
市场价：
¥2000.00
美元价：
1500.00
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
More Information
Alternate Name/Synonyms
Mutamycin; Ametycin; Mitocin-C; Mito-C; MMC
SKU
M-1108
CAS #
50-07-7
Chemical Name
[(4S,6S,7R,8S)-11-amino-7-methoxy-12-methyl-10,13-dioxo-2,5-diazatetracyclo[7.4.0.02,7.04,6]trideca-1(9),11-dien-8-yl]methyl carbamate
Chemical Formula
C15H18N4O5
Molecular Weight
334.3 Da
Appearance
Blue-violet solid
Purity
≥99%
Solubility
Clear blue-violet solution at 10 mg/mL in DMSO or CH3OH
Melting Point
N/A
Preparation
N/A
Storage Temp
-20°C, desiccated
THERAPEUTIC AREA
Oncological Disorders
USE
Mitomycin C is part of a family of azidine natural products. It is a DNA crosslinking and damaging agent, making it a useful antibiotic and antitumor compound. When crosslinking, Mitomycin C displays absolute specificity and high efficiency for the CpG sequence. Mammalian Cells treated with Mitomycin C (0.4 mg/mL for 5 min) can undergo apoptosis through upregulation of Bad, Fas, FasL and phosphorylated p53 along with activation of caspase-3, caspase-8, and caspase-9 activating both the intrinsic and extrinsic pathway for apoptosis.
MDL NUMBER
MFCD00078109
CHEMACX
X1004059-0
INCHI
InChI=1S/C15H18N4O5/c1-5-9(16)12(21)8-6(4-24-14(17)22)15(23-2)13-7(18-13)3-19(15)10(8)11(5)20/h6-7,13,18H,3-4,16H2,1-2H3,(H2,17,22)/t6-,7+,13+,15-/m1/s1
SMILES
CC1=C(C(=O)C2=C(C1=O)N3C[C@H]4[C@@H]([C@@]3([C@@H]2COC(=O)N)OC)N4)N
RTECS
CN0700000
UN #'S
UN 2811
PACKING GROUP
II
Handling
Use only in area provided with appropriate exhaust ventilation. Keep away from heat and source of ignition. Empty containers pose a fire risk, evaporate residue under fume hood. Ground all equipment containing material. Do not breathe dust.
Special Shipping
Yes
msds 1
M-1108, Mitomycin C, SDS, diamond format.pdf
Certificate of Analysis 1
M-1108, H1358A.pdf
Certificate of Analysis 2
M-1108, H1184D.pdf
Certificate of Analysis 3
M-1108, H1184C.pdf
品牌介绍
AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。
