AG Scientific/Concanomycin A/C-1057-
商品编号：
C-1057-
品牌：
agscientific
市场价：
¥2000.00
美元价：
1500.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MoreInformation
AlternateName/Synonyms
Folimycin;ConA;CMA
SKU
C-1057
CAS#
80890-47-7
ChemicalName
[(2R,3S,4R,6R)-6-[(2R,4R,5S,6R)-2-[(2S,3R,4S)-4-[(2R,3S,4E,6E,9R,10S,11S,12R,13R,14E,16Z)-11-ethyl-10,12-dihydroxy-3,17-dimethoxy-7,9,13,15-tetramethyl-18-oxo-1-oxacyclooctadeca-4,6,14,16-tetraen-2-yl]-3-hydroxypentan-2-yl]-2-hydroxy-5-methyl-6-[(E)-prop-
ChemicalFormula
C46H75NO14
MolecularWeight
866.1Da
Appearance
WhiteSolid
Purity
>98%
Solubility
SolubleinDSMO
MeltingPoint
N/A
Preparation
N/A
StorageTemp
-20°C,desiccated
THERAPEUTICAREA
NotAvailable
USE
ConcanamycinA,alsodesignatedfolimycin,isanantibioticandwell-notedspecificinhibitorofV-ATPase(vacuolartypeH+-ATPase)activity.ConcanamycinAisalsocapableofinducingcell-deaththroughapoptosis,abletoinhibitperforin-basedcytotoxicactivityinCD8+Tcells,andtoinhibitintracellularproteintraffickinginbothplantandanimalcells.AsaninhibitorofV-ATPase,concanamycinhasbeenreportedtoinducecelldeathviaapoptosisinWEHI231,SP2/0-Ag14cellslinesaswellasmousehybridomas.Theinhibitionofperforin-basedcytotoxicactivityinCD8+CTLcloneOE4wasreportedtobeselectiveforcompletelyblockingperforin-basedcytotoxicactivityintheseclones.Additionally,concanamycinAwasnotedtoleadtoreversIBLevacuolationoftheGolgiapparatusintobaccoBY-2cells,indicatingpotentialinterferencewithproteintraffickinginthiscellline.
MerckIndex
N/A
MDLNUMBER
MFCD00210037
CHEMACX
X1088871-6
INCHI
InChI=1S/C46H75NO14/c1-13-16-34-28(7)37(58-38-22-33(48)43(31(10)57-38)60-45(47)53)23-46(54,61-34)30(9)41(51)29(8)42-35(55-11)18-15-17-24(3)19-26(5)39(49)32(14-2)40(50)27(6)20-25(4)21-36(56-12)44(52)59-42/h13,15-18,20-21,26-35,37-43,48-51,54H,14,19,22-23H2,1-12H3,(H2,47,53)/b16-13+,18-15+,24-17+,25-20+,36-21-/t26-,27-,28-,29+,30+,31-,32+,33-,34-,35+,37-,38+,39+,40-,41-,42-,43-,46-/m1/s1
SMILES
CC[C@H]1[C@H]([C@@H](C/C(=C/C=C/[C@@H]([C@H](OC(=O)/C(=C/C(=C/[C@H]([C@H]1O)C)/C)/OC)[C@@H](C)[C@H]([C@H](C)[C@]2(C[C@H]([C@@H]([C@H](O2)/C=C/C)C)O[C@H]3C[C@H]([C@@H]([C@H](O3)C)OC(=O)N)O)O)O)OC)/C)C)O
Peptidesequence
NotApplicable
RTECS
CB9732000
UN#"S
UN3462
PACKINGGROUP
II
HAZARDCLASS
NotApplicable
Handling
Avoidcontactwithskin,eyesorclothing.Usepersonalprotectiveequipmentasrequired.Washcontaminatedclothingbeforereuse.Donotbreathedust/fume/gas/mist/vapors/spray.Donoteat,drinkorsmokewhenusingthisproduct.Usewithlocalexhaustventilation.Handleinaccordancewithgoodindustrialhygieneandsafetypractice.Corrosivehazard.Wearprotectivegloves/clothingandeye/faceprotection
MSDs1
C-1057,ConcanamycinA,SDS,diamondformat.pdf
CertificateofAnalysis1
C-1057,J1020A.pdf
CertificateofAnalysis2
C-1057,J1020.pdf
CertificateofAnalysis3
C-1057,G1245A.pdf
品牌介绍
AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。
