AG Scientific/Bischloroanthrabenzoxocinone/B-2553/2.5 mg
商品编号：
B-2553-2.5mg
品牌：
agscientific
市场价：
¥23305.20
美元价：
13983.12
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
*Please inquire the availability for this product. Bischloroanthrabenzoxocinone ((-)BABX) is a selective inhibitor of Type II fatty acid synthesis (FASII). BABX showed IC50 values of 11.4 and 35.3 α¼g/ml in the S. aureus and E. coli FASII assays, respectively, with comparable antibacterial activities. FASII is essential to bacterial cell viability and is a promising target for the development of novel antibiotics. More recently, BABX has been shown to inhibit agonist binding to Liver X receptors (LXR). These receptors regulate the expression of the ABCA1 gene, which mediates the efflux of cholesterol from cells.
Additional Information
| Synonyms | BABX |
|---|---|
| Product # | B-2553 |
| CAS # | 866022-28-8 |
| Formula | C28H24O7Cl2 |
| MW | 542.1 |
| Appearance | Light orange residue |
| Purity | >99% by HPLC |
| Solubility | Soluble in water (limited), ethanol, methanol, DMSO, and DMF |
| Boiling Point | 660.13 °C at 760 mmHg |
| Storage Temp | -20°C |
| Use | A selective inhibitor of Type II fatty acid synthesis (FASII) |
Additional Information
| MDL Number | MFCD14635432 |
|---|---|
| InChI | InChI=1S/C28H24Cl2O7/c1-10-6-12(35-5)8-14-15(10)26-16-11(9-28(4,36-14)37-26)7-13-17(22(16)31)23(32)18-19(27(13,2)3)20(29)25(34)21(30)24(18)33/h6-8,26,31,33-34H,9H2,1-5H3 |
| SMILES | C1(=C(C(=C(C6=C1C(C5=CC3=C(C4C2=C(C=C(C=C2OC(C3)(O4)C)OC)C)C(=C5C6=O)O[H])(C )C)O[H])Cl)O[H])Cl |
品牌介绍
AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。
