AG Scientific/Blasticin S HCl溶液在HEPES缓冲液中(10 mg/mL)/10x1 mL/B-1247-SOL-10x1 mL
商品编号:
B-1247-SOL-10x1ml
品牌:
agscientific
市场价:
¥4558.40
美元价:
3418.80
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
AlternateName/Synonyms
Bla-S;BlasticidinS
SKU
B-1247-SOL
CAS#
3513-03-9
ChemicalName
(2S,3S,6R)-3-[[(3S)-3-amino-5-[carbamimidoyl(methyl)amino]pentanoyl]amino]-6-(4-amino-2-oxopyrimidin-1-yl)-3,6-dihydro-2H-pyran-2-carboxylicacid;hydrochloride
ChemicalFormula
C17H26N8O5•HCl
MolecularWeight
458.9Da
Appearance
Clearsolution
Purity
≥98.0%
Solubility
Water:clearandfaintyellowsolution(5mg/mL)
StorageTemp
+4ºC,desiccated
THERAPEUTICAREA
Antibacterial
USE
Anucleosideantibioticsuppliedat10mg/mLinHEPESBufferforuseasaselectionantibiotic.BlasticidinSisanucleosideantibioticisolatedfromStreptomycesgriseochromogeneswhichinhibitsproteinsynthesisinbothprokaryoticandeukaryoticcells.BlasticidinSactsquicklybyinhibitingpeptidebondformationbytheribosome.ResistanceisconferredbyexpressionofoneoftwoBlasticidinSdeaminasegenes:BSDfromAspergillusterreusorbsrfromBacilluscereus.ThesedeaminasesconvertBlasticidinStoanontoxicdeaminohydroxyderivative.
MerckIndex
14,1316
MDLNUMBER
MFCD02091640
CHEMACX
X1339381-2
INCHI
InChI=1S/C17H26N8O5.ClH/c1-24(16(20)21)6-4-9(18)8-12(26)22-10-2-3-13(30-14(10)15(27)28)25-7-5-11(19)23-17(25)29;/h2-3,5,7,9-10,13-14H,4,6,8,18H2,1H3,(H3,20,21)(H,22,26)(H,27,28)(H2,19,23,29);1H
SMILES
[H]/N=C(N)/N(C)CCC(CC(=O)NC1C=CC(OC1C(=O)O)n2ccc(nc2=O)N)N.Cl
Handling
Avoidcontactwithskin,eyesorclothing.Usepersonalprotectiveequipmentasrequired.Washcontaminatedclothingbeforereuse.Donotbreathedust/fume/gas/mist/vapors/spray.Donoteat,drinkorsmokewhenusingthisproduct.
Citations
HumanApolipoproteinEIsRequiredforInfectivityandProductionofHepatitisCVirusinCellCulture,Kyung-SooChang,JieyunJiang,ZhaohuiCai,andGuangxiangLuo,J.Virol.,Dec2007;81:13783-13793.
Citations_Hyperlink
http://jvi.asm.org/cgi/reprint/81/24/13783
MSDs1
B-1247-SOL,BlasticidinSHClSolution,SDS,diamondformat.pdf
CertificateofAnalysis1
B-1247-SOL,J1105.pdf
CertificateofAnalysis2
B-1247-SOL,H1188.pdf
CertificateofAnalysis3
B-1247-SOL,H1183E.pdf
品牌介绍
AG Scientific, Inc.成立于1997年,专注于创新生化制剂以及用于诊断测试开发的定制原材料,以推进临床前研究药物开发。产品涉及抗生素,生物洗涤剂,缓冲液,诊断,酶,医疗设备试剂,蛋白酶K,还原剂,RNase A等。