AG Scientific/Dithiothreitol (DTT)/10 g/C-1029-10 g
商品编号：
C-1029-10g
品牌：
agscientific
市场价：
¥917.80
美元价：
688.35
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MoreInformation
AlternateName/Synonyms
DTT;Cleland"sReagent
SKU
C-1029
CAS#
3483-12-3
ChemicalName
(2S,3S)-1,4-bis(sulfanyl)butane-2,3-diol
ChemicalFormula
C4H10O2S2
MolecularWeight
154.25Da
Appearance
Whitecrystallinepowder
Purity
≥99.0%
Solubility
10%solutioninwater.Clearandcolorless
MeltingPoint
42-43°C
Preparation
N/A
StorageTemp
+4°C,underinertgas,desiccated
THERAPEUTICAREA
NotApplicable
USE
DTTisfrequentlyusedtoreducethedisulfidebondsofproteinsand,moregenerally,topreventintramolecularandintermoleculardisulfidebondsfromformingbetweencysteineresiduesofproteins.However,evenDTTcannotreduceburied(solvent-inaccessIBLe)disulfidebonds,soreductionofdisulfidebondsissometimescarriedoutunderdenaturingconditions(e.g.,athightemperatures,orinthepresenceofastrongdenaturantsuchas6Mguanidiniumchloride,8Murea,or1%sodiumdodecylsulfate).DTTisoftentimesusedalongwithsodiumdodecylsulfateinSDS-PAGEtofurtherdenatureproteinsbyreducingtheirdisulfidebondstoallowforbetterseparationofproteinsduringelectrophoresis.BecauseoftheABIlitytoreducedisulfidebonds,DTTcanbeusedtodenatureCD38onredbloodcells.Conversely,thesolventexposureofdifferentdisulfidebondscanbeassayedbytheirrateofreductioninthepresenceofDTT.DTTcanalsobeusedasanoxidizingagent.Itsprincipaladvantageisthateffectivelynomixed-disulfidespeciesarepopulated,incontrasttootheragentssuchasglutathione.Inveryrarecases,aDTTadductmaybeformed,i.e.,thetwosulfuratomsofDTTmayformdisulfidebondstodifferentsulfuratoms;insuchcases,DTTcannotcyclizesinceithasnosuchremainingfreethiols.
MerckIndex
12.3441.1996
MDLNUMBER
MFCD00004877
CHEMACX
X1009950-2
INCHI
InChI=1S/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m1/s1
SMILES
C([C@H]([C@@H](CS)O)O)S
RTECS
EK1610000
UN#"S
UN3335
PACKINGGROUP
III
Handling
Hygroscopic.Protectfrommoisture.Protectfromlight.Thepharmacologicalandtoxicologicalpropertiesofthisproducthavenotbeenfullyinvestigated.Usecautionwhenhandling.Donotusethiscompoundifyouarenotfullytrainedorareunawareofthehazardsinvolved.
MSDs1
C-1029,DTT,SDS,diamondformat.pdf
CertificateofAnalysis1
C-1029,J1220.pdf
CertificateofAnalysis2
C-1029,H1422B.pdf
CertificateofAnalysis3
C-1029,H1422A.pdf
品牌介绍
AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。
