AG Scientific/Chetomin/5 mg-查询/C-1443-5 mg-查询
商品编号：
C-1443-5mg-inquire
品牌：
agscientific
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
More Information
Alternate Name/Synonyms
Chaetomin; NSC 289491; s7939
SKU
C-1443
CAS #
1403-36-7
Chemical Name
(1S,3S,11R)-14-(hydroxymethyl)-3-[3-[[4-(hydroxymethyl)-5,7-dimethyl-6,8-dioxo-2,3-dithia-5,7-diazabicyclo[2.2.2]octan-1-yl]methyl]indol-1-yl]-18-methyl-15,16-dithia-10,12,18-triazapentacyclo[12.2.2.01,12.03,11.04,9]octadeca-4,6,8-triene-13,17-dione
Chemical Formula
C31H30N6O6S4
Molecular Weight
710.9 Da
Appearance
Off-white solid
Purity
>98% (HPLC)
Solubility
Soluble in DMSO, ethyl acetate or pyridin; fairly soluble in methanol, 100% ethanol; insoluble in water
Storage Temp
+4°C(short term); -20°C(long term)
THERAPEUTIC AREA
Oncological Disorders
USE
Chetomin, an antibiotic metabolite of chaetomium cochliodes, is an inhibitor of HIF-1 by weaken transcription of HIF-1 and recently is raised interests as a cancer chemotherapeutic agent.(Timothy R. Welch, 2013). Chetomin, a metabolite complex, produced by several fungi of the genus Chaetomium, disrupts the ability of tumours to adapt to hypoxia by blocking the HIF pathway.(Kung et al, 2004).
INCHI
ZRZWBWPDBOVIGQ-MRZRTKOQSA-N
Handling
Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Provide appropriate exhaust ventilation at places where dust is formed. Keep container tightly closed in a dry and well-ventilated place.
Certificate of Analysis 1
C-1443, G1228.pdf
Certificate of Analysis 2
C-1443, F1084A.pdf
Certificate of Analysis 3
C-1443, F1085.pdf
品牌介绍
AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。
