AG Scientific/Bleomycin Sulfate/10 mg/B-1269-10 mg
商品编号：
B-1269-10mg
品牌：
agscientific
市场价：
¥3075.00
美元价：
2306.25
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
More Information
Alternate Name/Synonyms
Bla-S; Blasticidin S
SKU
B-1247-SOL
CAS #
3513-03-9
Chemical Name
(2S,3S,6R)-3-[[(3S)-3-amino-5-[carbamimidoyl(methyl)amino]pentanoyl]amino]-6-(4-amino-2-oxopyrimidin-1-yl)-3,6-dihydro-2H-pyran-2-carboxylic acid;hydrochloride
Chemical Formula
C17H26N8O5•HCl
Molecular Weight
458.9 Da
Appearance
Clear solution
Purity
≥98.0%
Solubility
Water: clear and faint yellow solution (5 mg/mL)
Storage Temp
+4ºC, desiccated
THERAPEUTIC AREA
Antibacterial
USE
A nucleoside antibiotic supplied at 10 mg/mL in HEPES Buffer for use as a selection antibiotic. Blasticidin S is a nucleoside antibiotic isolated from Streptomyces griseochromogenes which inhibits protein synthesis in both prokaryotic and eukaryotic cells. Blasticidin S acts quickly by inhibiting peptide bond formation by the ribosome. Resistance is conferred by expression of one of two Blasticidin S deaminase genes: BSD from Aspergillus terreus or bsr from Bacillus cereus. These deaminases convert Blasticidin S to a nontoxic deaminohydroxy derivative.
Merck Index
14, 1316
MDL NUMBER
MFCD02091640
CHEMACX
X1339381-2
INCHI
InChI=1S/C17H26N8O5.ClH/c1-24(16(20)21)6-4-9(18)8-12(26)22-10-2-3-13(30-14(10)15(27)28)25-7-5-11(19)23-17(25)29;/h2-3,5,7,9-10,13-14H,4,6,8,18H2,1H3,(H3,20,21)(H,22,26)(H,27,28)(H2,19,23,29);1H
SMILES
[H]/N=C(N)/N(C)CCC(CC(=O)NC1C=CC(OC1C(=O)O)n2ccc(nc2=O)N)N.Cl
Handling
Avoid contact with skin, eyes or clothing. Use personal protective equipment as required. Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product.
Citations
Human Apolipoprotein E Is Required for Infectivity and Production of Hepatitis C Virus in Cell Culture, Kyung-Soo Chang, Jieyun Jiang, Zhaohui Cai, and Guangxiang Luo, J. Virol., Dec 2007; 81: 13783 - 13793.
Citations_Hyperlink
http://jvi.asm.org/cgi/reprint/81/24/13783
msds 1
B-1247-SOL, Blasticidin S HCl Solution, SDS, diamond format.pdf
Certificate of Analysis 1
B-1247-SOL, J1105.pdf
Certificate of Analysis 2
B-1247-SOL, H1188.pdf
Certificate of Analysis 3
B-1247-SOL, H1183E.pdf
品牌介绍
AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。
