AG Scientific/Apoptolidin/A-2631/0.5 mg
商品编号：
A-2631-0.5mg
品牌：
agscientific
市场价：
¥23920.40
美元价：
14352.24
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
*PleaseinquiretheavailABIlityforthisproduct.Apoptolidin,originallyisolatedfromaNocardiopsissp.,inducesapoptoticcelldeathinratglialcellstransformedwiththeadenovirusE1Aoncogene(IC50=11ng/ml).ApoptolidinisamongthemostselectivecytotoxicagentstestedbytheNCIinhumancancercelllines.AlthoughtheapoptoticactivityofapoptolidincorrelateswithF0F1-ATPaseinhibition,recentevidencesuggeststheexistenceofasecondaryBIOLOGicaltargetormorecomplexmodeofaction.
AdditionalInformation
| Product# | A-2631 |
|---|---|
| CAS# | 194874-06-1 |
| Formula | C58H96O21 |
| MW | 1129.4 |
| Appearance | WhiteLyophilisate |
| Purity | >95%byHPLC |
| Solubility | Solubleinethanol,methanol,DMF,andDMSO |
| BoilingPoint | 1108.92°Cat760mmHg |
| StorageTemp | -20°C |
| TherapeuticArea | OncologicalDisorders |
| Use | Apoptolidin,aselectivecytotoxicagent,isaninhibitorofF0F1-ATPaseuseincancercelllines |
| MDLNumber | MFCD09752711 |
|---|---|
| InChI | InChI=1S/C58H96O21/c1-29-17-16-18-40(59)43(69-13)25-45(76-55(65)33(5)23-31(3)21-30(2)22-32(4)41(20-19-29)77-56-51(63)50(62)52(71-15)37(9)74-56)53(64)58(67)35(7)48(60)34(6)42(79-58)24-39(28-68-12)75-47-27-57(11,66)54(38(10)73-47)78-46-26-44(70-14)49(61)36(8)72-46/h17,19-23,32,34-54,56,59-64,66-67H,16,18,24-28H2,1-15H3/b20-19+,29-17+,30-22+,31-21+,33-23+/t32-,34+,35-,36-,37+,38+,39-,40+,41-,42-,43+,44-,45+,46+,47+,48+,49-,50+,51+,52+,53-,54+,56+,57+,58-/m1/s1 |
| SMILES | O=C/5O[C@H]([C@@H](O)[C@]1(O)O[C@@H]([C@@H]([C@H](O)[C@H]1C)C)C[C@@H](O[C@@H]3O[C@@H](C)[C@H](O[C@@H]2O[C@H](C)[C@@H](O)[C@H](OC)C2)[C@](O)(C)C3)COC)C[C@H](OC)[C@@H](O)CC/C=C(/C=C/[C@@H](O[C@@H]4O[C@@H](C)[C@H](OC)[C@@H](O)[C@@H]4O)[C@@H](/C=C(/C=C(/C=C5C)C)C)C)C |
