AG Scientific/Borrelidin/1 mg/351.46
商品编号：
351.46
品牌：
agscientific
市场价：
¥0.00
美元价：
0.00
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
More Information
Alternate Name/Synonyms
Cyclopentanecarboxylic acid, NSC 216128, Treponemycin
SKU
B-1260
CAS #
7184-60-3
Chemical Name
2-(7-Cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4,6-dien-2-yl)-cyclopentanecarboxylic acid
Chemical Formula
C28H43NO6
Molecular Weight
489.6
Appearance
White to off white-beige crystalline powder
Purity
>98%
Solubility
May be dissolved in DMSO or Ethanol
Storage Temp
Store desiccated at -20°C
THERAPEUTIC AREA
Oncological Disorders
USE
Borrelidin, a small molecule nitrile-containing macrolide inhibitor of threonyl-tRNA synthetase, is a potent inducer of apoptosis in acute lymphoblastic leukemia.
MDL NUMBER
MFCD08276914
CHEMACX
X1533650-2
INCHI
InChI=1S/C28H43NO6/c1-17-12-18(2)14-20(4)27(32)21(16-29)8-5-6-11-25(22-9-7-10-23(22)28(33)34)35-26(31)15-24(30)19(3)13-17/h5-6,8,17-20,22-25,27,30,32H,7,9-15H2,1-4H3,(H,33,34)/b6-5+,21-8-/t17-,18+,19-,20-,22+,23+,24-,25-,27+/m0/s1
SMILES
C[C@H]1C[C@H](C[C@@H]([C@H](/C(=CC=CC[C@H](OC(=O)C[C@@H]([C@H](C1)C)O)[C@@H]2CCC[C@H]2C(=O)O)/C#N)O)C)C
Peptide sequence
Not Applicable
RTECS
ED8750000
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from light
Citations
Role of antibiotic ligand in nascent peptide-dependent ribosome stallingNora Vzquez-Laslop, Dorota Klepacki, Debbie C. Mulhearn, Haripriya Ramu, Olga Krasnykh, Scott Franzblau, and Alexander S. MankinPNAS, Jun 2011; 108: 10496 - 10501.
Citations_Hyperlink
http://www.pnas.org/cgi/reprint/108/26/10496
Certificate of Analysis 1
B-1260, G1128.pdf
Certificate of Analysis 2
B-1260, E1098B.pdf
Certificate of Analysis 3
B-1260, F1149B.pdf
品牌介绍
AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。
