AG Scientific/Alamethicin/10 mg/299.99
商品编号：
299.99
品牌：
agscientific
市场价：
¥0.00
美元价：
0.00
产品分类：
单克隆抗体
公司分类：
monoclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MoreInformation
AlternateName/Synonyms
AntibioticU-22324
SKU
A-1286
CAS#
27061-78-5
ChemicalName
(4S)-4-[[2-[[2-[[(2S)-2-[[(2S)-1-[2-[[(2S)-2-[[2-[[2-[[(2S)-2-[[2-[[(2S)-2-[[(2S)-2-[[2-[[(2S)-2-[[2-[[(2S)-1-(2-acetamido-2-methylpropanoyl)pyrrolidine-2-carbonyl]amino]-2-methylpropanoyl]amino]propanoyl]amino]-2-methylpropanoyl]amino]propanoyl]amino]-5-
ChemicalFormula
C92H150N22O25
MolecularWeight
1964.4Da
Appearance
Off-whitetobeigepowder
Purity
>99%byTLC
Solubility
DMSO:10mg/mLclearsolution;CH3OH:10mg/mLclearsolution
MeltingPoint
268-271°C
Preparation
StoreSolutionsat-20°Cforupto2months.
StorageTemp
-20°C
THERAPEUTICAREA
InfectiousDiseases
USE
Alamethicinisanantibioticthatfunctionsasamonovalentcationionophore.Ithasbeenusedtodevelopmethodsfortheroutineassessmentofpotentialnewdrugcandidatestoelicittheirpharmacokineticdruginteractions.Alamethicinformsvoltage-dependentionchannelsinthelipidbilayer,andthischannel-formingactivityhasbeenexploitedasatoolforintroducinghydrophilicsmallmoleculesintomitochondriawithoutdisruptingtheintegrityofthemembrane.
MerckIndex
N/A
MDLNUMBER
MFCD00151517
CHEMACX
X1009632-9
INCHI
InChI=1S/C92H150N22O25/c1-47(2)43-58(72(127)108-92(24,25)84(139)113-41-29-33-59(113)73(128)103-65(48(3)4)75(130)111-90(20,21)82(137)112-89(18,19)80(135)102-56(37-40-64(120)121)70(125)101-55(35-38-61(93)117)69(124)98-54(46-115)44-53-31-27-26-28-32-53)99-63(119)45-95-77(132)85(10,11)110-76(131)66(49(5)6)104-81(136)88(16,17)107-71(126)57(36-39-62(94)118)100-67(122)50(7)96-78(133)86(12,13)106-68(123)51(8)97-79(134)87(14,15)109-74(129)60-34-30-42-114(60)83(138)91(22,23)105-52(9)116/h26-28,31-32,47-51,54-60,65-66,115H,29-30,33-46H2,1-25H3,(H2,93,117)(H2,94,118)(H,95,132)(H,96,133)(H,97,134)(H,98,124)(H,99,119)(H,100,122)(H,101,125)(H,102,135)(H,103,128)(H,104,136)(H,105,116)(H,106,123)(H,107,126)(H,108,127)(H,109,129)(H,110,131)(H,111,130)(H,112,137)(H,120,121)/t50-,51-,54+,55-,56-,57-,58-,59-,60-,65-,66-/m0/s1
SMILES
C[C@@H](C(=O)N[C@@H](CCC(=O)N)C(=O)NC(C)(C)C(=O)N[C@@H](C(C)C)C(=O)NC(C)(C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)NC(C)(C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)NC(C)(C)C(=O)NC(C)(C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](Cc2ccccc2)CO)NC(=O)C(C
Peptidesequence
AC-AIB-PRO-AIB-ALA-AIB-ALA-GLN-AIB-VAL-AIB-GLY-LEU-AIB-PRO-VAL-AIB-AIB-GLU-GLN-PHENYLALANINOL
RTECS
NotApplicable
UN#"S
UN3288
PACKINGGROUP
III
HAZARDCLASS
NotApplicable
Handling
WARNING:TOXIC!Useonlyinareaprovidedwithappropriateexhaustventilation.Keepawayfromheatandsourceofignition.Emptycontainersposeafirerisk,evaporateresidueunderfumehood.Groundallequipmentcontainingmaterial.Donotbreathedust.
MSDs1
A-1286,Alamethicin,SDS,diamondformat.pdf
CertificateofAnalysis1
A-1286,J1079A.pdf
CertificateofAnalysis2
A-1286,J1079.pdf
CertificateofAnalysis3
A-1286,H1379.pdf
品牌介绍
AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。
