AG Scientific/Actinomycin D/10 mg/119.99
商品编号：
119.99
品牌：
agscientific
市场价：
¥0.00
美元价：
0.00
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
MoreInformation
AlternateName/Synonyms
ActinomycinIV;ActinomycinC1;Dactinomycin;Cosmegen;Meractinomycin;NCIC04682;NSC3053;OncostatinK;Glycopeptide,4a
SKU
A-1022
CAS#
50-76-0
ChemicalName
2-amino-4,6-dimethyl-3-oxo-1-N,9-N-bis[(3R,6S,7R,10S,16S)-7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazABIcyclo[14.3.0]nonadecan-6-yl]phenoxazine-1,9-dicarboxamide
ChemicalFormula
C62H86N12O16
MolecularWeight
1255.42Da
Appearance
Redtored-orangecrystallinepowder
Purity
>98%(HPLC,TLC)
Solubility
Clearorangesolutionat50mg/mLDMSOor10mg/mLMeOH
MeltingPoint
255-257°C
Preparation
N/A
StorageTemp
4°C,desiccated
THERAPEUTICAREA
OncologicalDisorders
USE
Forlaboratoryandresearchuseonly.ActinomycinDanditsfluorescentderivative,7-aminoactinomycinD(7-AAD),areusedasstainsinmicroscopyandflowcytometryapplications.Theaffinityofthesestains/compoundsforGC-richregionsofDNAstrandsmakesthemexcellentMarkersforDNA.7-AADbindstosinglestrandedDNA;thereforeitisausefultoolindeterminingapoptosisanddistinguishingbetweendeadcellsandliveones.
MerckIndex
12.2867.1996
MDLNUMBER
MFCD00005033
CHEMACX
X1005390-0
INCHI
InChI=1S/C62H86N12O16/c1-27(2)42-59(84)73-23-17-19-36(73)57(82)69(13)25-38(75)71(15)48(29(5)6)61(86)88-33(11)44(55(80)65-42)67-53(78)35-22-21-31(9)51-46(35)64-47-40(41(63)50(77)32(10)52(47)90-51)54(79)68-45-34(12)89-62(87)49(30(7)8)72(16)39(76)26-70(14)58(83)37-20-18-24-74(37)60(85)43(28(3)4)66-56(45)81/h21-22,27-30,33-34,36-37,42-45,48-49H,17-20,23-26,63H2,1-16H3,(H,65,80)(H,66,81)(H,67,78)(H,68,79)/t33-,34-,36+,37+,42-,43-,44+,45+,48+,49+/m1/s1
SMILES
C[C@@H]1[C@@H](C(=O)N[C@@H](C(=O)N2CCC[C@H]2C(=O)N(CC(=O)N([C@H](C(=O)O1)C(C)C)C)C)C(C)C)NC(=O)C3=C4C(=C(C=C3)C)OC5=C(C(=O)C(=C(C5=N4)C(=O)N[C@H]6[C@H](OC(=O)[C@@H](N(C(=O)CN(C(=O)[C@@H]7CCCN7C(=O)[C@H](NC6=O)C(C)C)C)C)C(C)C)C)N)C
RTECS
AU1575000
UN#"S
UN3462
PACKINGGROUP
II
Handling
Warning:VeryTOXIC.Forresearchuseonly.Notforhumanordruguse.Thepharmacologicalandtoxicologicalpropertiesofthisproducthavenotbeenfullyinvestigated.Usecautionwhenhandling.Donotusethiscompoundifyouarenotfullytrainedorareunawareofthehazardsinvolved.Avoidcontactwithskin,eyesorclothing.Usepersonalprotectiveequipmentasrequired.Washcontaminatedclothingbeforereuse.Donotbreathedust/fume/gas/mist/vapors/spray.Donoteat,drinkorsmokewhenusingthisproduct.
SpecialShipping
Yes
Citations
MEMBRANETRANSPORT,STRUCTURE,FUNCTION,ANDBIOGENESIS:RespiratorySyncytialVirusInhibitsLungEpithelialNa+ChannelsbyUp-regulatingInducIBLeNitric-oxideSynthaseWeifengSong,GangLiu,CharlesA.Bosworth,JohnR.Walker,GeorgeA.Megaw,AhmedLazrak,EdwardAbraham,WayneM.Sullender,andSADIsMatalonJ.Biol.Chem.,Mar2009;284:7294-7306.
Citations_Hyperlink
http://www.jbc.org/cgi/reprint/284/11/7294
MSDs1
A-1022,ActinomycinD,SDS,diamondformat.pdf
CertificateofAnalysis1
A-1022,J1130.pdf
CertificateofAnalysis2
A-1022,H1395.pdf
CertificateofAnalysis3
A-1022,H1254A.pdf
品牌介绍
AG Scientific, Inc.成立于1997年，专注于创新生化制剂以及用于诊断测试开发的定制原材料，以推进临床前研究药物开发。产品涉及抗生素，生物洗涤剂，缓冲液，诊断，酶，医疗设备试剂，蛋白酶K，还原剂，RNase A等。
