AG Scientific/麦考酚酸，MPA/M-1036/500 mg
商品编号：
M-1036-500mg
品牌：
agscientific
市场价：
¥3722.40
美元价：
2791.80
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Immunosuppressiveagent.Mycophenolicacid(MPA)hasbeentestedextensivelyinrenaltransplantpatientsandhasbeenshowntobeeffectiveinreducingtheincidenceofacutegraftrejection.MPAisnowbeingevaluatedincombinationswithtacrolimus.Itselectivelyinhibitslymphocyteproliferationbyblockingtheenzyme,inosinemonophosphatedehydrogenase,partofintheguanosinemonophosphatepathway.
Thisenzymeisinvolvedinthedenovosynthesisofpurinenucleotides1.
1.)Methanol-AssociatedMatrixEffectsinElectrosprayIonizationTandemMassSpectrometry.QuantificationofMycophenolicAcidandGlucuronideMetaboliteinHumanSerumbyHPLC-TandemMassSpectrometry.
AdditionalInformation
| Synonyms | MPA,mycophenolatemofetil(MMF) |
|---|---|
| Product# | M-1036 |
| CAS# | 24280-93-1 |
| ChemicalName | 6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-5-phthalanyl)-4-methyl-4-hexenoicacid |
| Formula | C17H20O6 |
| MW | 320.3 |
| Appearance | Whitetooff-whitePowder |
| Purity | 98% |
| Solubility | Solubleinethanol(>10mg/ml),DMSO(20mg/ml),DMF(30mg/ml),and1:1DMSO:PBS(pH7.2)(~0.5mg/ml).Insolubleinwater |
| MeltingPoint | 141°C |
| BoilingPoint | 611.61°Cat760mmHg |
| StorageTemp | +4°C |
| TherapeuticArea | AutoimmuneDiseases |
| Use | Mycophenolicacidisanimmunosuppressantdrugusedtopreventrejectioninorgantransplantation |
| MerckIndex | 13.6352.2001 |
|---|---|
| MDLNumber | MFCD00036814 |
| ChemACX | X1002405-4 |
| InChI | InChI=1S/C17H20O6/c1-9(5-7-13(18)19)4-6-11-15(20)14-12(8-23-17(14)21)10(2)16(11)22-3/h4,20H,5-8H2,1-3H3,(H,18,19) |
| SMILES | Cc1c2c(c(c(c1OC)CC=C(C)CCC(=O)O)O)C(=O)OC2 |
