AG Scientific/Pepstatin A，天冬氨酸蛋白酶抑制剂/P-1519/25 mg
商品编号：
P-1519-25mg
品牌：
agscientific
市场价：
¥2026.60
美元价：
1519.95
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
PepstatinAisacompetitive,reversIBLeasparticproteaseinhibitorandinhibitsproteasessuchaspepsin,chymosin,renin,HIVproteases,andcathepsinsDandE.Itishighlyselectiveandisoftenusedinamixturewithotherenzymeinhibitors.InvitrostudieshaveshownpepstatinAistheonlyasparticacidinhibitorthatexhibitsinhibitoryeffectsonHIVproteases.PepstatinAmayalsosuppressdifferentiationofosteoclastsbyinhibitingphosphorylationofMAPkinaseandinhibitingNFATc1expression. PepstatinAapplicationincoldinducibleRNA-bindingprotein(CIRP)viaCRISPR-Cas9system. PepstatinAinhibitslysosomalproteasesdirectly.
AdditionalInformation
| Synonyms | Isovaleryl-L-Val-L-Val-AHMHA-L-Ala-AHMHA(AHMHA=(3S,4S)-4-Amino-3-hydroxy-6-methyl-heptanoicacid) |
|---|---|
| Product# | P-1519 |
| CAS# | 26305-03-3 |
| ChemicalName | Isovaleryl-L-Val-L-Val-AHMHA-L-Ala-AHMHA(AHMHA=(3S,4S)-4-Amino-3-hydroxy-6-methyl-heptanoicacid) |
| Formula | C34H63N5O9 |
| MW | 685.9 |
| Appearance | WhiteSolid |
| Purity | 98% |
| Solubility | DMSO(5mg/ml)orMethanol(1mg/ml) |
| BoilingPoint | 997.6±65.0°Cat760mmHg |
| StorageTemp | -20°C |
| Use | PepstatinAisapotentreversibleinhibitorofasparticproteases. |
| MDLNumber | MFCD00060740 |
|---|---|
| ChemACX | X1036275-1 |
| InChI | InChI=1S/C34H63N5O9/c1-17(2)12-23(37-33(47)31(21(9)10)39-34(48)30(20(7)8)38-27(42)14-19(5)6)25(40)15-28(43)35-22(11)32(46)36-24(13-18(3)4)26(41)16-29(44)45/h17-26,30-31,40-41H,12-16H2,1-11H3,(H,35,43)(H,36,46)(H,37,47)(H,38,42)(H,39,48)(H,44,45)/t22-,23-,24-,25-,26-,30-,31-/m0/s1 |
| SMILES | C[C@@H](C(=O)N[C@@H](CC(C)C)[C@H](CC(=O)O)O)NC(=O)C[C@@H]([C@H](CC(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC(=O)CC(C)C)O |
| PeptideSequence | ISOVALERYL-VAL-VAL-STA-ALA-STA-OH |
