TurbochargedProteaseInhibitorCocktailisabroadspectrumProteaseInhibitorcocktailhasbeenspecificallydesignedtoprovidecompleteprotectionofvaluableproteinsofinterestfromdegradationduringextractionandpurification.
FeaturesandBenefits: Completeprotectionfromproteasesinonesinglecocktail.
AllourcocktailscontainAEBSF,thepreferredserineproteaseinhibitor,toprovidesuperiorprotectionwithunmatchedstABIlity,convenienceandreliability.
ThecocktailformulationsareavailablewithorwithoutEDTAwhichmayinterferewithproteinstabilityorcertaindownstreamapplications.
OurcocktailsarelyophilizedsolidswhichdissolveinstantaneouslymakingthemreADIlyavailablefortheirinstantaneousinhibitoryactionandareeasiertousethantabletsthatrequiresplitting,vortexingandtimeconsumingdissolution.
Ourlyophilizedsolidsareguaranteedforstability,reproducibilityandhaveashelflifeofoverayear.Mostothercommerciallyavailablecocktailsmadeandsoldinaqueoussolutionsofferverylowguaranteeofstabilityafter1monthofbeingmanufactured(Litref:Bestatin,Leupeptinsolutioninwaterarestablefor1monthat-20oC).
Economical:Morecosteffectivethanothercommerciallyavailableformulations.
Reliable:Countonourexpertiseintheproductionofhighqualitycocktailsthathavebeensuccessfullyusedfor20+yearsbythousandsofresearchersworldwide.
ProductDescription: WhiteLyophilizedSolid.Thecocktailcontains8inhibitorstargetingagainstthemajorclassesofproteasesasoutlinedinthefollowingtable.
Products | Target | Products | TargetProteases |
SerineProteases | CysteineProteasesandTrypsin-likeProteases | ||
BroadSpectrum,SerineProteases | AsparticProteases | ||
AminopeptidaseBandLeucineAminopeptidase | EDTA | Metalloproteases Metalloendopeptidases | |
CysteineProteases | Papain,CathepsinA/B |
PerformanceActivityAssay:ComparisonofourTurbochargedProteaseandPhosphataseInhibitorCocktailswithCompetitor’scommercialtablets.
Figure1:Usingageneralproteaseactivityassayandpancreasextract,ourTurbochargedCocktailsweretestedagainstCompetitor’scommerciallyavailabletabletsunderthesameconditions.Theresultswerebasedonproteaseactivityintheabsenceofanyinhibitorcocktails(Test1);comparedtoproteaseactivityinthepresenceofCompetitorsProteaseInhibitorTablets(Test2);TurbochargedProteaseInhibitorCocktail(T-2492/Test3);TurbochargedProtease+PhosphataseInhibitorCocktail(T-2495/Test4);andBlank
Figure2:Usingageneralphosphataseactivityassaythealkalinephosphataseactivitywasdeterminedwithnoinhibitorcocktailadded(Test1);comparedtoPhosphataseactivityinthepresenceofTurbochargedPhosphataseInhibitorCocktail(T-2494/Test2);TurbochargedProtease+PhosphataseInhibitorCocktail(T-2495/Test3);andBlank
TheresultsindicatethatourTurbochargedCocktailsshowedbetterperformance(>97%inhibition)thantheCompetitorsproductwithourTurbochargedProtease+PhosphataseinhibitorCocktailsbeingtheonlyoneofitskindavailableinthemarkettodayinhibitingbothProteases+Phosphatasesavailableasalyophilizedsolidinasinglevial.
AdditionalInformation
| Synonyms | TurbochargedProteaseInhibitorCocktail |
|---|---|
| Product# | T-2492 |
| Appearance | WhiteLyophilizedSolid |
| StorageTemp | -20ºC |
