ProductDescription: WhiteLyophilizedSolid.Thecocktailcontains16inhibitorstargetingagainstthemajorclassesofproteasesandphosphatasesasoutlinedinthefollowingtable
Products | TargetProteases | Products | TargetPhosphatases |
SerineProteases | Imidazole | AlkalinePhosphatases | |
BroadSpectrum,SerineProteases | SodiumOrthovanadate | ProteinTyrosinePhosphatase,AlkalinePhosphatase | |
AminopeptidaseBandLeucineAminopeptidase | SodiumMolyBDate | AcidandPhosphoproteinPhosphatases | |
CysteineProteases | NaF | AcidPhosphatases | |
CysteineProteasesandTrypsin-likeProteases | SodiumPyrophosphate | PP1andPP2A | |
AsparticProteases | Glycerophosphate | Ser/ThrPhosphatases | |
Metalloproteases Metalloendopeptidases | NaTartrateDihydrate | AcidPhosphatases | |
Papain,CathepsinA/B | Bromotetramisoleoxalate |
|
PerformanceActivityAssay: ComparisonofourTurbochargedProteaseandPhosphataseInhibitorCocktailswithCompetitor’scommercialtablets.
Figure1: Usingageneralproteaseactivityassayandpancreasextract,ourTurbochargedCocktailsweretestedagainstCompetitor’scommerciallyavailabletabletsunderthesameconditions.Theresultswerebasedonproteaseactivityintheabsenceofanyinhibitorcocktails(Test1);comparedtoproteaseactivityinthepresenceofCompetitorsProteaseInhibitorTablets(Test2);TurbochargedProteaseInhibitorCocktail(T-2492/Test3);TurbochargedProtease+PhosphataseInhibitorCocktail(T-2495/Test4);andBlank
Figure2: Usingageneralphosphataseactivityassaythealkalinephosphataseactivitywasdeterminedwithnoinhibitorcocktailadded(Test1);comparedtoPhosphataseactivityinthepresenceofTurbochargedPhosphataseInhibitorCocktail(T-2494/Test2);TurbochargedProtease+PhosphataseInhibitorCocktail(T-2495/Test3);andBlank
TheresultsindicatethatourTurbochargedCocktailsshowedbetterperformance(>97%inhibition)thantheCompetitorsproductwithourTurbochargedProtease+PhosphataseinhibitorCocktailsbeingtheonlyoneofitskindavailableinthemarkettodayinhibitingbothProteases+Phosphatasesavailableasalyophilizedsolidinasinglevial.
AdditionalInformation
Product# | T-2496 |
---|---|
Appearance | WhiteLyophilizedSolid.Hygroscopic |
Purity | SuitableforuseasProteaseandPhosphataseInhibitors |
Solubility | Solubleinwater,aqueousbuffersoradddirectlytoextractionmedia. |
StorageTemp | -20ºC |